Epidermal growth factor receptor (EGFR), the receptor for members of the epidermal growth
factor family, regulates cell proliferation and signal transduction; moreover, EGFR is related …

The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …

The EGFR family play a significant role in cell signal transduction and their overexpression
is implicated in the pathogenesis of numerous human solid cancers. Inhibition of the EGFR …

The present study established thirteen novel 8-hydroxyquinoline/chalcone hybrids 3a–m of
hopeful anticancer activity. According to NCI screening and MTT assay results, compounds …

In our overall goal to overcome the limitations associated with natural products for the
management of Alzheimer's disease and to develop in-vivo active multifunctional cholinergic …

Erratic cell proliferation is the initial symptom of cancer, which can eventually metastasize to
other organs. Before cancer becomes metastatic, its spread is triggered by pro-angiogenic …

Overexpression of the epidermal growth factor receptor (EGFR) has been linked to several
human cancers, including esophageal cancer, pancreatic cancer, anal cancer, breast …

Cancer continues to be a global health challenge, thereby necessitating the evolution of
innovative therapeutic strategies. The synthesis of chalcone derivatives has garnered …

Plants are an important source of drug development and numerous plant derived molecules
have been used in clinical practice for the ailment of various diseases. The Toll-like receptor …

Chalcones are members of the flavonoid family and act as intermediates in the biosynthesis
of flavonoids, which are widespread in plants. Meanwhile, chalcones are important …