Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

[HTML][HTML] Mesoporous silica nanoparticles for therapeutic/diagnostic applications

S Jafari, H Derakhshankhah, L Alaei, A Fattahi… - Biomedicine & …, 2019 - Elsevier
Based on unique intrinsic properties of mesoporous silica nanoparticles (MSNs) such as
high surface area, large pore size, good biocompatibility and biodegradability, stable …

[HTML][HTML] Mesoporous silica nanoparticles for drug and gene delivery

Y Zhou, G Quan, Q Wu, X Zhang, B Niu, B Wu… - … pharmaceutica sinica B, 2018 - Elsevier
Mesoporous silica nanoparticles (MSNs) are attracting increasing interest for potential
biomedical applications. With tailored mesoporous structure, huge surface area and pore …

Unlocking the potential of mesoporous silica nanoparticles in breast cancer treatment

R Thapa, H Ali, O Afzal, AA Bhat, WH Almalki… - Journal of Nanoparticle …, 2023 - Springer
Breast cancer is the most common cancer among women and is typically managed through
surgery, radiation therapy, and chemotherapy. However, chemotherapy drugs often lack …

An overview of chitin or chitosan/nano ceramic composite scaffolds for bone tissue engineering

S Deepthi, J Venkatesan, SK Kim… - International journal of …, 2016 - Elsevier
Chitin and chitosan based nanocomposite scaffolds have been widely used for bone tissue
engineering. These chitin and chitosan based scaffolds were reinforced with …

Immobilization of antibodies and enzymes on 3-aminopropyltriethoxysilane-functionalized bioanalytical platforms for biosensors and diagnostics

SK Vashist, E Lam, S Hrapovic, KB Male… - Chemical …, 2014 - ACS Publications
Biosensing and diagnostic platforms with high sensitivity, specificity, and fast response time
are based on immobilized biomolecules such as antibodies (Abs), aptamers, enzymes …

[HTML][HTML] MSC based gene delivery methods and strategies improve the therapeutic efficacy of neurological diseases

H Zhou, Y He, W Xiong, S Jing, X Duan, Z Huang… - Bioactive materials, 2023 - Elsevier
Mesenchymal stem cells (MSCs) are promising seed cells for neural regeneration therapy
owing to their plasticity and accessibility. They possess several inherent characteristics …

Extra-large pore mesoporous silica nanoparticles enabling co-delivery of high amounts of protein antigen and toll-like receptor 9 agonist for enhanced cancer vaccine …

BG Cha, JH Jeong, J Kim - ACS central science, 2018 - ACS Publications
Cancer vaccine aims to invoke antitumor adaptive immune responses to detect and
eliminate tumors. However, the current dendritic cells (DCs)-based cancer vaccines have …

Nanoparticles for bone tissue engineering

S Vieira, S Vial, RL Reis, JM Oliveira - Biotechnology progress, 2017 - Wiley Online Library
Tissue engineering (TE) envisions the creation of functional substitutes for damaged tissues
through integrated solutions, where medical, biological, and engineering principles are …

siRNA delivery using intelligent chitosan-capped mesoporous silica nanoparticles for overcoming multidrug resistance in malignant carcinoma cells

R Heidari, P Khosravian, SA Mirzaei, F Elahian - Scientific reports, 2021 - nature.com
Although siRNA is a promising technology for cancer gene therapy, effective cytoplasmic
delivery has remained a significant challenge. In this paper, a potent siRNA transfer system …