Biomaterials have had an increasingly important role in recent decades, in biomedical
device design and the development of tissue engineering solutions for cell delivery, drug …

When platelet numbers are low or when their function is disabled, the risk of bleeding is
high, which on the one hand indicates that in normal life vascular damage is a rather …

Antiplatelet treatment is of fundamental importance in combatting functions/dysfunction of
platelets in the pathogenesis of cardiovascular and inflammatory diseases. Dysfunction of …

Myelofibrosis is a severe myeloproliferative neoplasm characterized by increased numbers
of abnormal bone marrow megakaryocytes that induce fibrosis, destroying the hematopoietic …

After more than a century, aspirin remains one of the most commonly used drugs in western
medicine. Although mainly used for its anti-thrombotic, anti-pyretic, and analgesic properties …

Platelets have been hypothesized to promote certain neoplastic malignancies; however,
antiplatelet drugs are still not part of routine pharmacological cancer prevention and …

Current understanding of tumor immunosuppressive mechanisms forms the basis for
modern day immunotherapies. Immunoregulatory role of platelets in cancer remains largely …

The platelet proteome : Current Opinion in Hematology The platelet proteome : Current Opinion
in Hematology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts …

Integral membrane proteins (IMPs) lie at the critical junctions between intracellular
compartments and cells and their environment. As such, IMPs are in a unique position to …

Summary The glycoprotein VI (GPVI)–FcR γ‐chain complex initiates powerful activation of
platelets by the subendothelial matrix proteins collagen and laminin through an …