Neutrophils are the most abundant leukocytes in human peripheral blood. They form the first
line of defense against invading foreign pathogens and might play a crucial role in malaria …

Matrix metalloproteinases (MMPs) are associated with processes of tissue remodeling and
are expressed in all infections with protozoan parasites. We here report the status of MMP …

The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In
Plasmodium falciparum malaria, host and parasite processes can be assessed by dual RNA …

Matrix metalloproteinases (MMPs, matrixins) are a family of secreted and membrane-bound
zinc-dependent endopeptidases that have the combined capacity to degrade all the …

The predominant role of matrix metalloproteinase 8 in extracellular matrix turnover,
modulation of inflammatory responses and other physiological processes is well …

Parasitic protozoa are among the most important pathogens worldwide. Diseases such as
malaria, leishmaniasis, amoebiasis, giardiasis, trichomoniasis, and trypanosomiasis affect …

Transcriptomics, the analysis of genome-wide RNA expression, is a common approach to
investigate host and pathogen processes in infectious diseases. Technical and bioinformatic …

Cerebral malaria (CM) is a major cause of mortality in Plasmodium falciparum (Pf) infection
and is associated with the sequestration of parasitised erythrocytes in the microvasculature …

In animal model of experimental cerebral malaria (ECM), the genesis of neuropathology is
associated with oxidative stress and inflammatory mediators. There is limited progress in the …

Tissue inhibitor of metalloproteinases-1 (TIMP-1) exerts pleiotropic effects on cells including
conferring metastatic properties to cancer cells. As for metastatic cells, recent paradigms of …