[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Advances in computational methodologies for classification and sub-cellular locality prediction of non-coding RNAs

MN Asim, MA Ibrahim, M Imran Malik, A Dengel… - International Journal of …, 2021 - mdpi.com
Apart from protein-coding Ribonucleic acids (RNAs), there exists a variety of non-coding
RNAs (ncRNAs) which regulate complex cellular and molecular processes. High-throughput …

Convolutional neural networks for classification of alignments of non-coding RNA sequences

G Aoki, Y Sakakibara - Bioinformatics, 2018 - academic.oup.com
Motivation The convolutional neural network (CNN) has been applied to the classification
problem of DNA sequences, with the additional purpose of motif discovery. The training of …

The identification and functional annotation of RNA structures conserved in vertebrates

SE Seemann, AH Mirza, C Hansen… - Genome …, 2017 - genome.cshlp.org
Structured elements of RNA molecules are essential in, eg, RNA stabilization, localization,
and protein interaction, and their conservation across species suggests a common …

Structure-based screening for functional non-coding RNAs in fission yeast identifies a factor repressing untimely initiation of sexual differentiation

Y Ono, K Katayama, T Onuma, K Kubo… - Nucleic acids …, 2022 - academic.oup.com
Non-coding RNAs (ncRNAs) ubiquitously exist in normal and cancer cells. Despite their
prevalent distribution, the functions of most long ncRNAs remain uncharacterized. The …

Phylogenomic and comparative analysis of the distribution and regulatory patterns of TPP riboswitches in fungi

S Mukherjee, MD Retwitzer, D Barash, S Sengupta - Scientific reports, 2018 - nature.com
Riboswitches are metabolite or ion sensing cis-regulatory elements that regulate the
expression of the associated genes involved in biosynthesis or transport of the …

[PDF][PDF] Clusters of mammalian conserved RNA structures in UTRs associate with RBP binding sites

VP Gadekar, AW Munk, M Miladi… - NAR Genomics and …, 2024 - academic.oup.com
RNA secondary structures play essential roles in the formation of the tertiary structure and
function of a transcript. Recent genome-wide studies highlight significant potential for RNA …

Fast and precise prediction of non-coding RNAs (ncRNAs) using sequence alignment and k-mer counting

M Jha, R Gupta, R Saxena - International Journal of Information …, 2023 - Springer
Non-coding Ribonucleic acids (ncRNAs) are functional RNA molecules that transcribe from
DNA, but cannot be translated into proteins. These ncRNAs function to control the gene …

GraphClust2: annotation and discovery of structured RNAs with scalable and accessible integrative clustering

M Miladi, E Sokhoyan, T Houwaart, S Heyne… - …, 2019 - academic.oup.com
Background RNA plays essential roles in all known forms of life. Clustering RNA sequences
with common sequence and structure is an essential step towards studying RNA function …

Identification of RNA 3´ ends and termination sites in Haloferax volcanii

SJ Berkemer, LK Maier, F Amman, SH Bernhart… - RNA biology, 2020 - Taylor & Francis
Archaeal genomes are densely packed; thus, correct transcription termination is an
important factor for orchestrated gene expression. A systematic analysis of RNA 3´ termini, to …