Background Breast cancer is the most prevalent cancer among women worldwide and the
fifth cause of death among all cancer patients. Breast cancer development is driven by …

Cancer stem cells (CSCs) are a subset of highly tumorigenic cells in tumors. They have
enhanced self-renewal properties, are usually chemo-radioresistant, and can promote tumor …

Simple Summary Chordomas and chondrosarcomas are rare tumors that can occur within
the skull base and spinal column and are often resistant to chemotherapy and radiation …

Rare cancers (RCs), which account for over 20% of cancer cases, face significant research
and treatment challenges due to their limited prevalence. This results in suboptimal …

Chordoma is a rare type of bone cancer characterized by its locally aggressive and
destructive behavior. Chordoma is located in one of the three primary regions: skull …

Background Chordomas are rare, slow-growing and locally aggressive bone sarcomas. At
present, chordomas are difficult to manage due to their high recurrence rate, metastasis …

There are few studies on the mechanism of pituitary adenoma (PA) destroying bone. The
current study aimed to investigate the role of MEG8/miR-454-3p/TNF-α in bone-invasive …

Chronic allograft dysfunction (CAD) is a major factor that hinders kidney transplant survival
in the long run. Epithelial–mesenchymal transition (EMT) has been confirmed to significantly …

Introduction and objective Despite the improvements in management and treatment of
chordomas over time, the risk of disease recurrence remains high. Consequently, there is a …

Background The complement inhibitor CSMD1 acts as a tumor suppressor in various types
of solid cancers. Despite its high level of expression in the brain, its function in gliomas …