Evolving approaches to profiling the microbiome in skin disease

Y Chen, R Knight, RL Gallo - Frontiers in Immunology, 2023 - frontiersin.org
Despite its harsh and dry environment, human skin is home to diverse microbes, including
bacteria, fungi, viruses, and microscopic mites. These microbes form communities that may …

Time of sample collection is critical for the replicability of microbiome analyses

C Allaband, A Lingaraju, S Flores Ramos, T Kumar… - Nature …, 2024 - nature.com
As the microbiome field moves from descriptive and associative research to mechanistic and
interventional studies, being able to account for all confounding variables in the …

Best practice for wildlife gut microbiome research: A comprehensive review of methodology for 16S rRNA gene investigations

L Combrink, IR Humphreys, Q Washburn… - Frontiers in …, 2023 - frontiersin.org
Extensive research in well-studied animal models underscores the importance of
commensal gastrointestinal (gut) microbes to animal physiology. Gut microbes have been …

Critical assessment of metagenome interpretation: the second round of challenges

F Meyer, A Fritz, ZL Deng, D Koslicki, TR Lesker… - Nature …, 2022 - nature.com
Evaluating metagenomic software is key for optimizing metagenome interpretation and focus
of the Initiative for the Critical Assessment of Metagenome Interpretation (CAMI). The CAMI II …

A comparison of six DNA extraction protocols for 16S, ITS and shotgun metagenomic sequencing of microbial communities

JP Shaffer, CS Carpenter, C Martino, RA Salido… - …, 2022 - Taylor & Francis
Microbial communities contain a broad phylogenetic diversity of organisms; however, the
majority of methods center on describing bacteria and archaea. Fungi are important …

Gut microbiome signatures and host colonization with multidrug-resistant bacteria

NS Isles, A Mu, JC Kwong, BP Howden… - Trends in Microbiology, 2022 - cell.com
The human gut is host to a diverse range of microorganisms that offer protection against
colonization by multidrug-resistant bacteria. Antibiotic use, medications, health conditions …

Integration of 168,000 samples reveals global patterns of the human gut microbiome

RJ Abdill, SP Graham, V Rubinetti, M Ahmadian… - Cell, 2023 - cell.com
The factors shaping human microbiome variation are a major focus of biomedical research.
While other fields have used large sequencing compendia to extract insights requiring …

Serum and CSF metabolomics analysis shows Mediterranean Ketogenic Diet mitigates risk factors of Alzheimer's disease

A Schweickart, R Batra, BJ Neth, C Martino… - NPJ Metabolic Health …, 2024 - nature.com
Alzheimer's disease (AD) is influenced by a variety of modifiable risk factors, including a
person's dietary habits. While the ketogenic diet (KD) holds promise in reducing metabolic …

Diet–Gut Microbiota Relations: Critical Appraisal of Evidence From Studies Using Metagenomics

M Lotankar, N Houttu, K Mokkala, K Laitinen - Nutrition Reviews, 2024 - academic.oup.com
Diet may influence the gut microbiota and subsequently affect the host's health. Recent
developments in methods analyzing the composition and function of the gut microbiota allow …

The impact of freezing on the post-mortem human microbiome

N Ogbanga, A Nelson, S Gino, DJ Wescott… - Frontiers in Ecology …, 2023 - frontiersin.org
Introduction Human donations are often used in forensic research as they can provide
unique insights into post-mortem research that cannot be obtained with animal proxies. This …