Transient receptor potential (TRP) channels are one primary type of calcium (Ca 2+)
permeable channels, and those relevant transmembrane and intracellular TRP channels …

Transient receptor potential (TRP) channels comprise a diverse family of ion channels, the
majority of which are calcium permeable and show sophisticated regulatory patterns in …

Cell migration is a key process in cancer metastasis, allowing malignant cells to spread from
the primary tumor to distant organs. At the molecular level, migration is the result of several …

Mechanical forces are an inherent element in the world around us. The effects of their action
can be observed both on the macro and molecular levels. They can also play a prominent …

Over the past two decades, the treatment of cancer has been revolutionised by the highly
successful introduction of novel molecular targeted therapies and immunotherapies …

The transient receptor potential melastatin subfamily member 2 (TRPM2), a thermo and
reactive oxygen species (ROS) sensitive Ca2+-permeable cation channel has a vital role in …

Microglia maintain central nervous system homeostasis by monitoring changes in their
environment (resting state) and by taking protective actions to equilibrate such changes …

Cancer is caused by excessive cell proliferation and a propensity to avoid cell death, while
the spread of cancer is facilitated by enhanced cellular migration, invasion, and …

Metastasis is the hallmark of failed tumor treatment and is typically associated with death
due to cancer. Transient receptor potential (TRP) channels affect changes in intracellular …

The channels from the superfamily of transient receptor potential (TRP) activated by reactive
oxygen species (ROS) can be defined as redox channels. Those with the best exposure of …