The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …

Central serous chorioretinopathy (CSCR) is a major cause of vision threat among middle-
aged male individuals. Multimodal imaging led to the description of a wide range of CSCR …

Systemic arterial hypertension is the most important modifiable risk factor for all-cause
morbidity and mortality worldwide and is associated with increased risk of cardiovascular …

The RAAS through its physiological effectors plays a key role in promoting and maintaining
inflammation. Inflammation is an important mechanism in the development and progression …

Background: Aldosterone plays a detrimental role on the cardiovascular system and PA
patients display a higher risk of events compared with EH. Objectives: The objectives of the …

The discovery of steroid hormone receptors in brain regions that mediate every aspect of
brain function has broadened the definition of 'neuroendocrinology'to include the reciprocal …

Central serous chorioretinopathy (CSCR) is a vision-threatening eye disease with no
validated treatment and unknown pathogeny. In CSCR, dilation and leakage of choroid …

Hypertension is a cardiovascular risk factor present in over two-thirds of people over age 60
in North America; elevated blood pressure correlates with increased risk of heart attack …

Klotho is a potent regulator of 1, 25-hydroxyvitamin D3 [1, 25 (OH) 2D3] formation and
calcium-phosphate metabolism. Klotho-hypomorphic mice (kl/kl mice) suffer from severe …

Two-thirds of adults in the US are overweight or obese, and another 26 million have type 2
diabetes (T2D). Patients with diabetes and/or the metabolic syndrome have a significantly …