Q fever immunology: the quest for a safe and effective vaccine

G Sam, J Stenos, SR Graves, BHA Rehm - npj Vaccines, 2023 - nature.com
Q fever is an infectious zoonotic disease, caused by the Gram-negative bacterium Coxiella
burnetii. Transmission occurs from livestock to humans through inhalation of a survival form …

Protective effect of Schistosoma japonicum eggs on TNBS-induced colitis is associated with regulating Treg/Th17 balance and reprogramming glycolipid metabolism …

X Hou, F Zhu, W Zheng, ML Jacques… - Frontiers in Cellular …, 2022 - frontiersin.org
Inflammatory bowel diseases (IBDs) have been classified as modern refractory diseases.
However, safe, well-tolerated, and effective treatments for IBDs are still lacking. Therefore …

miR-615 facilitates porcine epidemic diarrhea virus replication by targeting IRAK1 to inhibit type III interferon expression

H Zheng, C Li, X Zhu, WX Wang, B Yin… - Frontiers in …, 2022 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV) in the Coronavirus family is a highly contagious
enteric pathogen in the swine industry, which has evolved mechanisms to evade host innate …

Puerarin alleviates sleep disorders in aged mice related to repairing intestinal mucosal barrier

Q Tao, J Zhang, Q Liang, S Song, S Wang… - Natural Products and …, 2023 - Springer
More and more evidence suggests that puerarin, a potential remedy for gut inflammation,
may have an ameliorative effect on sleep disturbances. However, the relationship between …

[HTML][HTML] Orientia tsutsugamushi infection stimulates Syk-dependent responses and innate cytosolic defenses in macrophages

J Fisher, C Gonzales, Z Chroust, Y Liang, L Soong - Pathogens, 2023 - mdpi.com
Orientia tsutsugamushi is an obligately intracellular bacterium and an etiological agent of
scrub typhus. Human studies and animal models of scrub typhus have shown robust type 1 …

Identification and Characterization of Antigenic Properties of Schistosoma japonicum Heat Shock Protein 90α Derived Peptides

C Shen, X Zhu, X Xu, H Chang, Y Ni, C Li, K He… - Pathogens, 2022 - mdpi.com
It is known that schistosome-derived antigens induce innate and adaptive immune
responses that are essential for the formation of hepatic immunopathology. Here, we …

New advances in obligate intracellular bacteria: pathogenesis and host interactions

J Jiao, J Wang, J Fu - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
Chlamydia) are an important and fascinating group of microorganisms, as they are often
pathogenic to humans and represent a significant public health burden worldwide (Fisher et …

FtsK Regulates the Assembly of the Division Machinery in the FtsZ-Less Chlamydia trachomatis

MKK Harpring - 2024 - search.proquest.com
In evolving to obligate intracellular dependence, Chlamydia trachomatis serovar L2 (Ct), has
eliminated several gene products essential for cell division in most other bacteria, including …

Vaccine-induced adaptive T cell immunity enhances protective responses against Coxiella burnetii

S Jan - 2023 - search.proquest.com
Coxiella burnetii is an intracellular Gram-negative bacterium responsible for Q fever, a
zoonotic disease with significant global health implications courtesy of its endemic status …