Cyanine conjugate‐based biomedical imaging probes

Y Li, Y Zhou, X Yue, Z Dai - Advanced Healthcare Materials, 2020 - Wiley Online Library
Cyanine is a class of fluorescent dye with meritorious fluorescence properties and has
motivated numerous researchers to explore its imaging capabilities by miscellaneous …

Doubly Strapped Zwitterionic NIR‐I and NIR‐II Heptamethine Cyanine Dyes for Bioconjugation and Fluorescence Imaging

DH Li, RS Gamage, AG Oliver, NL Patel… - Angewandte …, 2023 - Wiley Online Library
Heptamethine cyanine dyes enable deep tissue fluorescence imaging in the near infrared
(NIR) window. Small molecule conjugates of the benchmark dye ZW800‐1 have been tested …

Heptamethine cyanine–based application for cancer theranostics

L Zhang, H Jia, X Liu, Y Zou, J Sun, M Liu… - Frontiers in …, 2022 - frontiersin.org
Cancer is the most common life-threatening malignant disease. The future of personalized
cancer treatments relies on the development of functional agents that have tumor-targeted …

Synthesis and preclinical characterization of the PSMA-targeted hybrid tracer PSMA-I&F for nuclear and fluorescence imaging of prostate cancer

M Schottelius, A Wurzer, K Wissmiller… - Journal of Nuclear …, 2019 - Soc Nuclear Med
The prostate-specific membrane antigen (PSMA)–targeted radiotracers 68Ga/177Lu-PSMA-
I&T and 99mTc-PSMA-I&S (for i maging and s urgery) are currently successfully used for …

Trending: radioactive and fluorescent bimodal/hybrid tracers as multiplexing solutions for surgical guidance

FWB van Leeuwen, M Schottelius… - Journal of Nuclear …, 2020 - Soc Nuclear Med
By contributing to noninvasive molecular imaging and radioguided surgery, nuclear
medicine has been instrumental in the realization of precision medicine. During the last …

Hybrid tracers based on cyanine backbones targeting prostate-specific membrane antigen: tuning pharmacokinetic properties and exploring dye–protein interaction

AW Hensbergen, T Buckle… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Prostate cancer surgery is currently being revolutionized by the use of prostate-specific
membrane antigen (PSMA)–targeted radiotracers, for example, 99mTc-labeled PSMA tracer …

The current status and future prospects for molecular imaging-guided precision surgery

I Boekestijn, MN van Oosterom, P Dell'Oglio… - Cancer Imaging, 2022 - Springer
Molecular imaging technologies are increasingly used to diagnose, monitor, and guide
treatment of ie, cancer. In this review, the current status and future prospects of the use of …

Fluorescent dye labeling changes the biodistribution of tumor-targeted nanoparticles

P Álamo, V Pallarès, MV Céspedes, A Falgàs… - Pharmaceutics, 2020 - mdpi.com
Fluorescent dye labeling is a common strategy to analyze the fate of administered
nanoparticles in living organisms. However, to which extent the labeling processes can alter …

High-contrast detection of somatostatin receptor subtype-2 for fluorescence-guided surgery

S Hernandez Vargas, S AghaAmiri… - Molecular …, 2022 - ACS Publications
Dye design can influence the ability of fluorescently labeled imaging agents to generate
tumor contrast and has become an area of significant interest in the field of fluorescence …

Fluorescent labeling of biocompatible block copolymers: Synthetic strategies and applications in bioimaging

S Bou, AS Klymchenko, M Collot - Materials advances, 2021 - pubs.rsc.org
Among biocompatible materials, block copolymers (BCPs) possess several advantages due
to the control of their chemistry and the possibility of combining various blocks with defined …