[HTML][HTML] Circulating tumour DNA alterations: emerging biomarker in head and neck squamous cell carcinoma

X Huang, PHG Duijf, S Sriram, G Perera… - Journal of biomedical …, 2023 - Springer
Head and Neck cancers (HNC) are a heterogeneous group of upper aero-digestive tract
cancer and account for 931,922 new cases and 467,125 deaths worldwide. About 90% of …

[HTML][HTML] Liquid biopsy to detect minimal residual disease: methodology and impact

N Honoré, R Galot, C van Marcke, N Limaye… - Cancers, 2021 - mdpi.com
Simple Summary The field of liquid biopsy is rapidly evolving. Techniques that improve
accuracy are constantly being developed, and clinicians increasingly use liquid biopsy as a …

[HTML][HTML] Applicability of liquid biopsies to represent the mutational profile of tumor tissue from different cancer entities

S Liebs, T Eder, F Klauschen, M Schütte, ML Yaspo… - Oncogene, 2021 - nature.com
Genetic investigation of tumor heterogeneity and clonal evolution in solid cancers could be
assisted by the analysis of liquid biopsies. However, tumors of various entities might release …

Personalizing surveillance in head and neck cancer

GJ Hanna, N Patel, SG Tedla, KL Baugnon… - American Society of …, 2023 - ascopubs.org
Head and neck squamous cell carcinoma (HNSCC) encompasses a spectrum of
heterogeneous diseases originating in the oral cavity, pharynx, and larynx. Within the United …

[HTML][HTML] The promise of circulating tumor DNA in head and neck cancer

SS Aulakh, DA Silverman, K Young, SK Dennis… - Cancers, 2022 - mdpi.com
Simple Summary Head and neck cancer remains a challenging and deadly disease as it is
often identified in more advanced stages due to limitations in screening and surveillance …

[HTML][HTML] Resection margins in head and neck cancer surgery: an update of residual disease and field cancerization

AS Pierik, CR Leemans, RH Brakenhoff - Cancers, 2021 - mdpi.com
Simple Summary Curative treatment of head and neck squamous cell carcinoma (HNSCC)
is largely dependent on locoregional control of the disease. However, HNSCCs frequently …

Individualized circulating tumor DNA monitoring in head and neck squamous cell carcinoma

R Kogo, T Manako, T Iwaya, S Nishizuka… - Cancer …, 2022 - Wiley Online Library
There is no useful biomarker to evaluate treatment response and early relapse in head and
neck squamous cell carcinoma (HNSCC). Circulating tumor DNA (ctDNA) is a promising …

[HTML][HTML] Liquid biopsies based on cell-free DNA as a potential biomarker in head and neck cancer

Ó Rapado-González, AM Rodríguez-Ces… - … Dental Science Review, 2023 - Elsevier
In the era of 'precision medicine', liquid biopsies based on cell-free DNA (cfDNA) have
emerged as a promising tool in the oncology field. cfDNA from cancer patients is a mixture of …

[HTML][HTML] Longitudinal detection of somatic mutations in saliva and plasma for the surveillance of oral squamous cell carcinomas

Y Cui, HS Kim, ES Cho, D Han, JA Park, JY Park… - PloS one, 2021 - journals.plos.org
Purposes Although clinical and radiological examinations can be used to diagnose oral
cancer, and surgical pathology remains the gold standard, these conventional methods …

[HTML][HTML] Management of HPV-related squamous cell carcinoma of the head and neck: pitfalls and caveat

F Perri, F Longo, F Caponigro, F Sandomenico… - Cancers, 2020 - mdpi.com
Head and neck squamous cell carcinomas (HNSCCs) are a very heterogeneous group of
malignancies arising from the upper aerodigestive tract. They show different clinical …