From the field to the laboratory: Controlling DNA contamination in human ancient DNA research in the high-throughput sequencing era
Abstract High-Throughput DNA Sequencing (HTS) technologies have changed the way in
which we detect and assess DNA contamination in ancient DNA studies. Researchers use …
which we detect and assess DNA contamination in ancient DNA studies. Researchers use …
Evolution of human apolipoprotein E (APOE) isoforms: Gene structure, protein function and interaction with dietary factors
P Huebbe, G Rimbach - Ageing research reviews, 2017 - Elsevier
Apolipoprotein E (APOE) is a member of the vertebrate protein family of exchangeable
apolipoproteins that is characterized by amphipathic α-helices encoded by multiple …
apolipoproteins that is characterized by amphipathic α-helices encoded by multiple …
The Prevotella copri complex comprises four distinct clades underrepresented in westernized populations
Prevotella copri is a common human gut microbe that has been both positively and
negatively associated with host health. In a cross-continent meta-analysis exploiting> 6,500 …
negatively associated with host health. In a cross-continent meta-analysis exploiting> 6,500 …
Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans
Despite broad agreement that the Americas were initially populated via Beringia, the land
bridge that connected far northeast Asia with northwestern North America during the …
bridge that connected far northeast Asia with northwestern North America during the …
Early human dispersals within the Americas
JV Moreno-Mayar, L Vinner, P de Barros Damgaard… - Science, 2018 - science.org
INTRODUCTION Genetic studies of the Pleistocene peopling of the Americas have focused
on the timing and number of migrations from Siberia into North America. They show that …
on the timing and number of migrations from Siberia into North America. They show that …
Earliest human presence in North America dated to the last glacial maximum: new radiocarbon dates from Bluefish Caves, Canada
The timing of the first entry of humans into North America is still hotly debated within the
scientific community. Excavations conducted at Bluefish Caves (Yukon Territory) from 1977 …
scientific community. Excavations conducted at Bluefish Caves (Yukon Territory) from 1977 …
Bison phylogeography constrains dispersal and viability of the Ice Free Corridor in western Canada
The Ice Free Corridor has been invoked as a route for Pleistocene human and animal
dispersals between eastern Beringia and more southerly areas of North America. Despite …
dispersals between eastern Beringia and more southerly areas of North America. Despite …
A genomic view of the peopling of the Americas
P Skoglund, D Reich - Current opinion in genetics & development, 2016 - Elsevier
Whole-genome studies have documented that most Native American ancestry stems from a
single population that diversified within the continent more than twelve thousand years ago …
single population that diversified within the continent more than twelve thousand years ago …
Beringia and the global dispersal of modern humans
JF Hoffecker, SA Elias, DH O'Rourke… - … : Issues, news, and …, 2016 - Wiley Online Library
Until recently, the settlement of the Americas seemed largely divorced from the out‐of‐Africa
dispersal of anatomically modern humans, which began at least 50,000 years ago. Native …
dispersal of anatomically modern humans, which began at least 50,000 years ago. Native …
Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk
Because of the ubiquitous adaptability of our material culture, some human populations
have occupied extreme environments that intensified selection on existing genomic …
have occupied extreme environments that intensified selection on existing genomic …