In 2015, oncolytic virotherapy was approved for clinical use, and in 2017, recombinant
adeno-associated virus (AAV) delivery was also approved. However, systemic …

Immunotherapy is regarded as one of the most promising approaches for treating tumors,
with a multitude of immunotherapeutic thoughts currently under consideration for the lethal …

Tumors employ diverse strategies for immune evasion. Unraveling the mechanisms by
which tumors suppress anti-tumor immunity facilitates the development of immunotherapies …

Background Lipid metabolism has been implicated in a variety of normal cellular processes
and strongly related to the development of multiple diseases, including tumor. Tumor …

Reciprocal interactions between the tumor microenvironment (TME) and cancer cells play
important roles in tumorigenesis and progression of glioma. Glioma-associated …

Cholesterol is an essential membrane component, and the metabolites from cholesterol play
important biological functions to intricately support cancer progression and dampen immune …

Lipid metabolism in cancer cells has garnered increasing attention in recent decades.
Cancer cells thrive in hypoxic conditions, nutrient deficiency, and oxidative stress and …

Oncolytic viruses (OVs) for cancer treatment are in a rapid stage of development, and the
direct tumor lysis and activation of a comprehensive host immune response are …

Cell proliferation and function require nutrients, energy, and biosynthesis activity to duplicate
repertoires for each daughter. It is therefore not surprising that tumor microenvironment …

Despite the discovery and prevalent clinical use of potent lipid-lowering therapies, including
statins and PCSK9 inhibitors, cardiovascular diseases (CVD) caused by atherosclerosis …