Morphogenesis is one of the most remarkable examples of biological pattern formation.
Despite substantial progress in the field, we still do not understand the organizational …

Recognizing the crucial role of mechanical regulation and forces in tissue development and
homeostasis has stirred a demand for in situ measurement of forces and stresses. Among …

The basement membrane (BM) is a specialized extracellular matrix (ECM), which underlies
or encases developing tissues. Mechanical properties of encasing BMs have been shown to …

Mechanics is known to play a fundamental role in many cellular and developmental
processes. Beyond active forces and material properties, osmotic pressure is believed to …

The basement membrane (BM) is an extracellular matrix that plays important roles in animal
development. A spatial heterogeneity in composition and structural properties of the BM …

Fluid-filled biological cavities are ubiquitous, but their collective dynamics has remained
largely unexplored from a physical perspective. Based on experimental observations in …

Cooperative morphogenesis of cell lineages underlies the development of functional units
and organs. To study mechanisms driving the coordination of lineages, we investigated …

From insects to mice, oocytes develop within cysts alongside nurse-like sister germ cells.
Prior to fertilization, the nurse cells' cytoplasmic contents are transported into the oocyte …

The process by which biological systems such as cells, tissues and organisms acquire
shape has been named as morphogenesis and it is central to a plethora of biological …

Cephalic furrow formation (CFF) is a major morphogenetic movement during gastrulation in
Drosophila melanogaster embryos that gives rise to a deep, transitory epithelial …