[HTML][HTML] Towards hepatitis C virus elimination: Egyptian experience, achievements and limitations

D Omran, M Alboraie, RA Zayed, MN Wifi… - World journal of …, 2018 - ncbi.nlm.nih.gov
Worldwide, more than one million people die each year from hepatitis C virus (HCV) related
diseases, and over 300 million people are chronically infected with hepatitis B or C. Egypt …

Sustained virologic response to direct-acting antiviral therapy in patients with chronic hepatitis C and hepatocellular carcinoma: a systematic review and meta-analysis

F Ji, YH Yeo, MT Wei, E Ogawa, M Enomoto… - Journal of …, 2019 - Elsevier
Background & Aims The effect of hepatocellular carcinoma (HCC) on the response to
interferon-free direct-acting antiviral (DAA) therapy in patients with chronic hepatitis C (CHC) …

Generic daclatasvir plus sofosbuvir, with or without ribavirin, in treatment of chronic hepatitis C: real‐world results from 18 378 patients in Egypt

H Omar, W El Akel, T Elbaz, M El Kassas… - Alimentary …, 2018 - Wiley Online Library
Background Treatment of chronic hepatitis C using combination of sofosbuvir (SOF) and
daclatasvir (DCV) was used in several clinical trials and multicentre studies, which were …

Planning and prioritizing direct-acting antivirals treatment for HCV patients in countries with limited resources: lessons from the Egyptian experience

A Elsharkawy, M El-Raziky, W El-Akel, K El-Saeed… - Journal of …, 2018 - Elsevier
Background and Aims The introduction of direct-acting antivirals for hepatitis C virus (HCV)
in Egypt led to massive treatment uptake, with Egypt's national HCV treatment program …

Eliminating hepatitis C within low-income countries–The need to cure genotypes 4, 5, 6

T Asselah, T Hassanein, I Waked, A Mansouri… - Journal of …, 2018 - Elsevier
Around 70 to 100 million people are chronically infected with HCV worldwide. HCV antiviral
drug development has revolutionised the treatment of HCV, with several direct-acting …

Systematic review with meta‐analysis: effectiveness of direct‐acting antiviral treatment for hepatitis C in patients with hepatocellular carcinoma

S He, I Lockart, M Alavi, M Danta… - Alimentary …, 2020 - Wiley Online Library
Background Direct‐acting antiviral (DAA) therapy for hepatitis C virus (HCV) infection is
highly curative and tolerable. Among patients with hepatocellular carcinoma (HCC), optimal …

Impact of different sofosbuvir based treatment regimens on the biochemical profile of chronic hepatitis C genotype 4 patients

A Elsharkawy, R Eletreby, R Fouad… - Expert review of …, 2017 - Taylor & Francis
Background: Huge efforts have been made to control chronic HCV in Egypt with introduction
of Direct-Acting Antivirals (DAAs). Current study aims at evaluating effect of various DAA …

An account of the real-life hepatitis C management in a single specialized viral hepatitis treatment centre in Egypt: results of treating 7042 patients with 7 different …

M El Kassas, M Alboraie, D Omran… - Expert Review of …, 2018 - Taylor & Francis
Background: A large Egyptian treatment program for HCV was launched in2014 after the
introduction of direct-acting antiviral agents (DAAs). This program depended mainly on …

Sofosbuvir‐containing regimens are safe and effective in the treatment of HCV patients with moderate to severe renal impairment

R Eletreby, M El‐Serafy, M Anees, G Kasem… - Liver …, 2020 - Wiley Online Library
Abstract Background and Aims This study aimed to assess the safety and efficacy of
sofosbuvir (SOF)‐based regimens in patients with moderate to severe renal impairment; a …

Treatment with direct‐acting antiviral agents of hepatitis C virus infection in injecting drug users: A prospective study

L Boglione, S Mornese Pinna, A De Nicolò… - Journal of viral …, 2017 - Wiley Online Library
In this prospective study, we evaluated the effectiveness and tolerability of novel therapies
against hepatitis C virus (HCV) in a cohort of PWID enrolled at our centre from April 2015 to …