Partial least squares (PLS) is an efficient statistical regression technique that is highly suited
for the analysis of genomic and proteomic data. In this article, we review both the theory …

Metabolomics, the global quantitative assessment of metabolites in a biological system, has
played a pivotal role in various fields of science in the post-genomic era. Metabolites are the …

Polycystic ovary syndrome (PCOS) is characterized by androgen excess, ovulatory
dysfunction and polycystic ovaries, and is often accompanied by insulin resistance. The …

Objective The initial colonisation of the human microbiota and the impact of maternal health
on neonatal microbiota at birth remain largely unknown. The aim of our study is to …

This study compares the application of two variable selection methods in partial least
squares regression (PLSR), the variable importance in projection (VIP) method and the …

Recent reports have suggested the involvement of gut microbiota in the progression of
colorectal cancer (CRC). We utilized pyrosequencing based analysis of 16S rRNA genes to …

Both genetic variations and diet-disrupted gut microbiota can predispose animals to
metabolic syndromes (MS). This study assessed the relative contributions of host genetics …

Plasmodium infections result in clinical presentations that range from asymptomatic to
severe malaria, resulting in∼ 1 million deaths annually. Despite this toll on humanity, the …

The characteristics of the OPLS method have been investigated for the purpose of
discriminant analysis (OPLS‐DA). We demonstrate how class‐orthogonal variation can be …

论文基于MODIS-NDVI 数据, DEM 及气象数据, 辅以趋势分析, 多元回归残差法,
偏最小二乘回归法, 反演了秦岭地区2000—2015 年植被覆盖度及分析了其“格局—过程—趋势” …