Current progress in the derivation and therapeutic application of neural stem cells

Y Tang, P Yu, L Cheng - Cell death & disease, 2017 - nature.com
Neural stem cells (NSCs) have a unique role in neural regeneration. Cell therapy based on
NSC transplantation is a promising tool for the treatment of nervous system diseases …

G-protein-coupled receptors in adult neurogenesis

VA Doze, DM Perez - Pharmacological reviews, 2012 - ASPET
The importance of adult neurogenesis has only recently been accepted, resulting in a
completely new field of investigation within stem cell biology. The regulation and functional …

One mouse, two cultures: isolation and culture of adult neural stem cells from the two neurogenic zones of individual mice

TL Walker, G Kempermann - JoVE (Journal of Visualized Experiments), 2014 - jove.com
The neurosphere assay and the adherent monolayer culture system are valuable tools to
determine the potential (proliferation or differentiation) of adult neural stem cells in vitro …

Growth Differentiation Factor 11 treatment leads to neuronal and vascular improvements in the hippocampus of aged mice

C Ozek, RC Krolewski, SM Buchanan, LL Rubin - Scientific reports, 2018 - nature.com
Aging is the biggest risk factor for several neurodegenerative diseases. Parabiosis
experiments have established that old mouse brains are improved by exposure to young …

The RNA binding protein IMP2 preserves glioblastoma stem cells by preventing let-7 target gene silencing

N Degrauwe, TB Schlumpf, M Janiszewska, P Martin… - Cell reports, 2016 - cell.com
Cancer stem cells (CSCs) can drive tumor growth, and their maintenance may rely on post-
transcriptional regulation of gene expression, including that mediated by microRNAs …

Brain-derived neurotrophic factor (BDNF) role in cannabinoid-mediated neurogenesis

FF Ferreira, FF Ribeiro, RS Rodrigues… - Frontiers in cellular …, 2018 - frontiersin.org
The adult mammalian brain can produce new neurons in a process called adult
neurogenesis, which occurs mainly in the subventricular zone (SVZ) and in the hippocampal …

Enriched environment promotes adult hippocampal neurogenesis through FGFRs

M Grońska-Pęski, JT Gonçalves… - Journal of …, 2021 - Soc Neuroscience
The addition of new neurons to existing neural circuits in the adult brain remains of great
interest to neurobiology because of its therapeutic implications. The premier model for …

[PDF][PDF] Establishing embryonic mouse neural stem cell culture using the neurosphere assay

H Azari, S Sharififar, M Rahman, S Ansari… - J Vis Exp, 2011 - researchgate.net
In mammalians, stem cells acts as a source of undifferentiated cells to maintain cell genesis
and renewal in different tissues and organs during the life span of the animal. They can …

Subventricular zone-derived extracellular vesicles promote functional recovery in rat model of spinal cord injury by inhibition of NLRP3 inflammasome complex …

I Mohammed, S Ijaz, T Mokhtari, M Gholaminejhad… - Metabolic brain …, 2020 - Springer
Spinal cord injury (SCI) is the destruction of spinal cord motor and sensory resulted from an
attack on the spinal cord, which can cause significant physiological damage. The …

Curcumin as a double-edged sword for stem cells: dose, time and cell type-specific responses to curcumin

F Attari, M Zahmatkesh, H Aligholi, SE Mehr… - DARU Journal of …, 2015 - Springer
Background The beneficial effects of curcumin which includes its antioxidant, anti-
inflammatory and cancer chemo-preventive properties have been identified. Little …