Epidemiology of Parkinson's disease—East versus West

MM Abbas, Z Xu, LCS Tan - Movement disorders clinical …, 2018 - Wiley Online Library
Background The cause of PD at present remains unknown. A number of epidemiological
studies have been conducted across the globe to ascertain the disease burden and the …

Microbial infections are a risk factor for neurodegenerative diseases

SK Lotz, BM Blackhurst, KL Reagin… - Frontiers in Cellular …, 2021 - frontiersin.org
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, comprise a family of disorders characterized by progressive …

[HTML][HTML] Upregulation of α-synuclein following immune activation: Possible trigger of Parkinson's disease

A Kasen, C Houck, AR Burmeister, Q Sha… - Neurobiology of …, 2022 - Elsevier
Abstract Alpha-synuclein (α-syn) has been suggested to have many functions including,
vesicle transport in neurons, transcriptional regulator, modulator of immune cell maturation …

AGE-RAGE axis culminates into multiple pathogenic processes: A central road to neurodegeneration

R Bhattacharya, MR Alam, MA Kamal… - Frontiers in Molecular …, 2023 - frontiersin.org
Advanced glycation end-products (AGEs; eg, glyoxal, methylglyoxal or carboxymethyl-
lysine) are heterogenous group of toxic compounds synthesized in the body through both …

[HTML][HTML] Microbes and Parkinson's disease: from associations to mechanisms

T Cannon, S Gruenheid - Trends in Microbiology, 2022 - cell.com
Parkinson's disease (PD) is a neurodegenerative disorder influenced by both genetic and
environmental factors. The mechanisms leading to neurodegeneration in PD are still under …

Association of antiviral therapy with risk of Parkinson disease in patients with chronic hepatitis C virus infection

WY Lin, MS Lin, YH Weng, TH Yeh, YS Lin… - JAMA …, 2019 - jamanetwork.com
Importance Epidemiologic evidence suggests that hepatitis C virus (HCV) could be a risk
factor for Parkinson disease (PD), but treatment for HCV infection has never been …

Infectious Agents as Potential Drivers of α‐Synucleinopathies

M Linard, A Ravier, L Mougué, I Grgurina… - Movement …, 2022 - Wiley Online Library
Abstract α‐synucleinopathies, encompassing Parkinson's disease, dementia with Lewy
bodies, and multiple system atrophy, are devastating neurodegenerative diseases for which …

[HTML][HTML] Safety and efficacy of sofosbuvir plus velpatasvir with or without ribavirin for chronic hepatitis C virus infection: a systematic review and meta-analysis

H Ahmed, AI Abushouk, A Attia, M Gadelkarim… - Journal of infection and …, 2018 - Elsevier
Velpatasvir is a newly FDA-approved inhibitor of hepatitis C virus (HCV) NS5A protein. We
performed this systematic review and meta-analysis to investigate the safety and efficacy of …

Role of hepatitis c virus in hepatocellular carcinoma and neurological disorders: an overview

M Suhail, SS Sohrab, MA Kamal, EI Azhar - Frontiers in Oncology, 2022 - frontiersin.org
The hepatitis C virus (HCV) causes serious issues, affecting 71 million people globally. The
most common manifestations range from chronic hepatitis to liver cirrhosis, leading to …

Antiviral therapy in patients with chronic hepatitis C is associated with a reduced risk of parkinsonism

TH Su, HC Yang, TC Tseng, SW Chou… - Movement …, 2019 - Wiley Online Library
Background The risk of parkinsonism after antiviral treatment against chronic hepatitis C
(CHC) is unclear. Objectives To investigate the association between CHC and parkinsonism …