Chemotaxis enables microorganisms to move according to chemical gradients. Although
this process requires substantial cellular energy, it also affords key physiological benefits …

Vaccines are the pharmaceutical products that offer the best cost‐benefit ratio in the pre‐-
vention or treatment of diseases. In that a vaccine is a pharmaceutical product, vaccine …

Bacterial cell surface adhesins play a major role in facilitating host colonization and
subsequent establishment of infection. The surface of Mycobacterium tuberculosis, owing to …

The identification of easily measured, accurate diagnostic biomarkers for active tuberculosis
(TB) will have a significant impact on global TB control efforts. Because of the host and …

Mycobacterium tuberculosis, the primary causative agent of tuberculosis, infects
macrophages and transforms the hostile intracellular environment into a permissive niche …

The genome of Mycobacterium tuberculosis (Mtb) harbors the genetic machinery for
assembly of the F imbrial l ow-molecular-weight p rotein (Flp) type IV pilus. Presumably, the …

Objective: The aim of this study was to investigate the effect of pre-treatment with curcumin
on metabolic changes induced by two different pathophysiological mechanisms in rats …

Mycobacterium tuberculosis (Mtb) adhesin proteins are promising candidates for subunit
vaccine design. Multi-epitope Mtb vaccine and diagnostic candidates were designed using …

Bacterial N-acetylmuramoyl-l-alanine amidases are cell-wall hydrolases that hydrolyze the
bond between N-acetylmuramic acid and l-alanine in cell-wall glycopeptides. Rv3717 of …

Adherence, colonization, and survival of mycobacteria in host cells require surface
adhesins, which are attractive pharmacotherapeutic targets. A large arsenal of pilus and non …