TrackMate 7: integrating state-of-the-art segmentation algorithms into tracking pipelines

D Ershov, MS Phan, JW Pylvänäinen, SU Rigaud… - Nature …, 2022 - nature.com
TrackMate is an automated tracking software used to analyze bioimages and is distributed
as a Fiji plugin. Here, we introduce a new version of TrackMate. TrackMate 7 is built to …

[HTML][HTML] Assessing cell migration in hydrogels: An overview of relevant materials and methods

AA Solbu, D Caballero, S Damigos, SC Kundu… - Materials Today Bio, 2023 - Elsevier
Cell migration is essential in numerous living processes, including embryonic development,
wound healing, immune responses, and cancer metastasis. From individual cells to …

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini… - Nature, 2016 - nature.com
Mutations of the tricarboxylic acid cycle enzyme fumarate hydratase cause hereditary
leiomyomatosis and renal cell cancer. Fumarate hydratase-deficient renal cancers are …

Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin

D Andreev, M Liu, D Weidner, K Kachler… - The Journal of …, 2020 - Am Soc Clin Investig
Although the control of bone-resorbing osteoclasts through osteocyte-derived RANKL is well
defined, little is known about the regulation of osteoclasts by osteocyte death. Indeed …

Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing

JR Holt, WZ Zeng, EL Evans, SH Woo, S Ma… - Elife, 2021 - elifesciences.org
Keratinocytes, the predominant cell type of the epidermis, migrate to reinstate the epithelial
barrier during wound healing. Mechanical cues are known to regulate keratinocyte re …

Bringing TrackMate into the era of machine-learning and deep-learning

D Ershov, MS Phan, JW Pylvänäinen, SU Rigaud… - BioRxiv, 2021 - biorxiv.org
TrackMate is an automated tracking software used to analyze bioimages and distributed as
a Fiji plugin. Here we introduce a new version of TrackMate rewritten to improve …

Properties of immature and mature dendritic cells: phenotype, morphology, phagocytosis, and migration

MK Kim, J Kim - RSC advances, 2019 - pubs.rsc.org
Dendritic cells (DCs) are antigen-presenting cells that play an important role in connecting
the innate and adaptive immunity of the immune system. To mediate innate and adaptive …

Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells

K Srpan, A Ambrose, A Karampatzakis, M Saeed… - Journal of Cell …, 2018 - rupress.org
Natural Killer (NK) cells can engage multiple virally infected or tumor cells sequentially and
deliver perforin for cytolytic killing of these targets. Using microscopy to visualize …

Coordinated integrin activation by actin-dependent force during T-cell migration

P Nordenfelt, HL Elliott, TA Springer - Nature communications, 2016 - nature.com
For a cell to move forward it must convert chemical energy into mechanical propulsion.
Force produced by actin polymerization can generate traction across the plasma membrane …

Bioelectronic microfluidic wound healing: a platform for investigating direct current stimulation of injured cell collectives

S Shaner, A Savelyeva, A Kvartuh, N Jedrusik… - Lab on a Chip, 2023 - pubs.rsc.org
Upon cutaneous injury, the human body naturally forms an electric field (EF) that acts as a
guidance cue for relevant cellular and tissue repair and reorganization. However, the direct …