In the era of multi-omic sciences, dogma on singular cause-effect in physio-pathological
processes is overcome and system biology approaches have been providing new …

Currently, immune checkpoint inhibitors (ICIs) are widely considered the standard initial
treatment for advanced non-small cell lung cancer (NSCLC) when there are no targetable …

Background: A crucial part of the malignant processes of soft tissue sarcoma (STS) is played
by cuproptosis and lncRNAs. However, the connection between cuproptosis-related …

Background Kidney renal clear cell carcinoma (KIRC) is a common malignant tumor of the
urinary system. This study aims to develop new biomarkers for KIRC and explore the impact …

Background Lung cancer is a high-incidence cancer, and it is also the most common cause
of cancer death worldwide. 80–85% of lung cancer cases can be classified as non-small cell …

Objective In China, lung cancer ranks first in both incidence and mortality among all
malignant tumors. Non-small cell lung cancer (NSCLC) constitutes the vast majority of …

Background: Clinical biomarkers, allow better classification of patients according to their
disease risk, prognosis, and/or response to treatment. Although affordable omics-based …

Colorectal cancer (CRC) is a major global health concern, with a significant impact on
morbidity and mortality. The molecular mechanisms underlying CRC, especially DNA …

Background Chronic obstructive pulmonary disease (COPD) is a chronic and progressive
lung disease. Disulfidptosis-related genes (DRGs) may be involved in the pathogenesis of …

Simple Summary The tumor microenvironment (TME) influences treatment outcome, and
analysis of immune cell composition plays an important role in establishing effective …