Cancer is a complex disease resulting from abnormal cell growth that is induced by a
number of genetic and environmental factors. The tumor microenvironment (TME), which …

Tissue-resident macrophages are key players in inflammatory processes, and their
activation and functionality are crucial in health and disease. Numerous diseases are …

The pervasive role of the innate immune system is established by interferons. Emerging
research shows an underappreciated ability of macrophages to regulate and propagate …

Acute lung injury (ALI) is a pulmonary disorder that causes acute respiratory failure, thus
leading to relative high mortality worldwide. However, the molecular mechanisms of ALI …

Expression of the key anti-inflammatory cytokine IL-10 in lipopolysaccharide (LPS)-
stimulated macrophages is mediated by a delayed autocrine/paracrine loop of type I …

Although 3-aminopropyl functionalized magnesium phyllosilicate nanoparticles (hereafter
aminoclay nanoparticles, ACNs) are well-known nanomaterials employed as drug carriers …

Correlations between circulating cytokine levels and disease states are well established,
and pharmacological modulation of the immune response is thus an important aspect of the …

Urinary bladder cancer (BCa), a high ranked and common cancer around the world is a
great concern for the global public health systems. Although our knowledge has been …

Gut microbiota can coordinate with different tissues and organs to maintain human health,
which derives the concept of the gut-X axis. Conversely, the dysbiosis of gut microbiota …

Introduction: While TLR ligands derived from microbial flora and pathogens are important
activators of the innate immune system, a variety of factors such as intracellular bacteria …