Overproduction of oxidants (reactive oxygen species and reactive nitrogen species) in the
human body is responsible for the pathogenesis of some diseases. The scavenging of these …

Objective Saffron as a natural product has long been used to impede and treat different
disorders including cardiovascular disease (CVDs). Stigma is the most principal part of …

Free radicals or reactive oxygen species (ROS) generated from various sources in the
environment as well as from cellular processes in the body are of serious health challenges …

Background Diabetes-induced oxidative stress has an essential role in hepatic dysfunction.
The current study was aimed to potentiate the impact of crocin treatment on the anti-oxidant …

Obesity is associated with various diseases, particularly diabetes, hypertension,
osteoarthritis and heart disease. Research on possibilities of herbal extracts and isolated …

Crocus sativus L.(saffron) is widely used as a traditional spice for flavoring, coloring and
medicinal purposes. As a traditional Chinese herb, saffron promotes blood circulation …

Aim The clinical application of the chemotherapeutic agent; Doxorubicin (DOX) is limited by
its toxic effects on several body organs. The current study was conducted to evaluate the …

Doxorubicin (DOX) is a well-known chemotherapeutic drug for most malignancies including
breast cancer and leukemia whilst the usage of DOX is limited owing to its cardiotoxicity. In …

Crocin and crocetin in rat plasma were simultaneously analysed using ultra-performance
liquid chromatography tandem mass spectroscopy (UPLC–MS/MS), and method was fully …

Osteoblast apoptosis has been identified as an important event in the development of
glucocorticoid (GC)‑induced osteoporosis and osteonecrosis of the femoral head. Crocin, a …