Abstract Allopregnanolone, a 3α, 5α‐progesterone metabolite, acts as a potent allosteric
modulator of the γ‐aminobutyric acid type A receptor. In the present review, the synthesis of …

GABA A receptors containing the α6 subunit are highly expressed in cerebellar granule cells
and less abundantly in many other neuronal and peripheral tissues. Here, we for the first …

Ziziphus jujuba var. spinosa (Bunge) Hu ex HF. Chow [Rhamnaceae; Ziziphi Spinosae
Semen (ZSS)] has attracted extensive attention as the first choice of traditional Chinese …

General anesthetics are a class of drugs that target the central nervous system and are
widely used for various medical procedures. General anesthetics produce many behavioral …

Neuroscience offers important insights into the pathogenesis and treatment of obesity by
investigating neural circuits underpinning appetite and feeding. Gamma-aminobutyric acid …

Introduction Medications which target benzodiazepine (BZD) binding sites of GABAA
receptors (GABAARs) have been in widespread use since the nineteen-sixties. They carry …

Neuroscientists have historically examined obesity through the lens of food addiction. This
thesis instead explored how a neuroinflammation lens of obesity development may …

Epilepsy is one of the most common brain disorders affecting people of all ages with a
growing global incidence of at least 1%(GBD 2016 Epilepsy Collaborators, 2019; Thurman …

Several reports have been published over recent years about Zolpidem's paradoxical
arousing effect in unresponsive wakefulness syndrome (UWS) and minimally conscious …

Abstract Ziziphi Spinosae Semen (ZSS), as the first choice of traditional Chinese medicine in
the treatment of insomnia, has attracted extensive attention. However, the current studies on …