Design, synthesis and bio-evaluation of indolin-2-ones as potential antidiabetic agents
Background: Diabetes mellitus is a serious global health concern, and this is expected to
impact more than 300 million people by 2025. The current study focuses on identifying …
impact more than 300 million people by 2025. The current study focuses on identifying …
Molecular docking, synthesis and biological evaluation (enzyme inhibition, antimicrobial and antioxidant) of methoxy benzoin/benzil/stilbenoid derivatives
In this study. methoxy benzoin compounds (1-10) were synthesized from the corresponding
aromatic aldehydes based on a screening of biological activity. Oxidation and reduction of …
aromatic aldehydes based on a screening of biological activity. Oxidation and reduction of …
Synthesis of new 5-iodoisatin derivatives: Predicting antioxidant inhibition activity with DFT studies
MS Çavuş - Journal of Molecular Structure, 2025 - Elsevier
Abstract New 5-iodoisatin-aryl/alkyl/thiosemicarbazones (1–8) were synthesized from
various isocyanates and 5-iodoisatin, and their structures were validated by spectroscopic …
various isocyanates and 5-iodoisatin, and their structures were validated by spectroscopic …
Design, synthesis, and enzyme inhibition evaluation of some novel Mono-and Di-O-ß-D-Glycopyranosyl Chalcone analogues with molecular docking studies
In this study, some novel mono-and di-O-β-D-glycopyranosyl chalcone analogs were
designed, synthesized, and characterized. The chalcone derivatives were synthesized with …
designed, synthesized, and characterized. The chalcone derivatives were synthesized with …
一种N-杂环卡宾催化合成氘代苯偶姻的方法
张心予， 耿慧慧， 张士磊， 王卫， 陈晓蓓 - 有机化学, 2023 - sioc-journal.cn
有机化学 Page 1 有机化学 Chinese Journal of Organic Chemistry ARTICLE * Corresponding
authors. E-mail: wwang@pharmacy.arizona.edu; xiaobei@ecust.edu.cn Received October 6 …
authors. E-mail: wwang@pharmacy.arizona.edu; xiaobei@ecust.edu.cn Received October 6 …
MW Assisted Synthesis of New 4, 6-diaryl-3, 4-Didhydropyrimidines-2 (1H)-thione Derivatives: Tyrosinase Inhibition, Antioxidant, and Molecular Docking Studies
A number of new methoxy-substituted 4, 6-diaryl-3, 4-dihydropyrimidine-2 (1H)-thiones (DH-
Pyr-S, 17-28) were designed and synthesized by the reaction of methoxy-substituted …
Pyr-S, 17-28) were designed and synthesized by the reaction of methoxy-substituted …
Electrostatic Potential Mapped onto Electron Density Surface, ADME, Molecular Docking and Molecular Dynamics Simulations of Some Indolin-2-one Analogues as …
IE Otuokere - 2024 - researchsquare.com
The transfer of cytochrome c (cyt c) from the mitochondria to the cytosol is commonly
regarded as the final stage in the mitochondria-mediated apoptotic response, where there is …
regarded as the final stage in the mitochondria-mediated apoptotic response, where there is …
A Method for the Synthesis of Deuterated Benzoins Catalyzed by N-Heterocyclic Carbene
Z Xinyu, G Huihui, Z Shilei, W Wei… - Chinese Journal of …, 2023 - sioc-journal.cn
An efficient method has been developed for the synthesis of deuterated benzoins from two
molecules of aldehydes under the catalysis of N-heterocyclic carbene by using D 2 O as the …
molecules of aldehydes under the catalysis of N-heterocyclic carbene by using D 2 O as the …
Benzimidazole-thiazole hybrids; synthesis, structure elucidation and cytotoxic properties
Aim: Neuroblastoma is one of the leading tumors among the childhood cancers and the
treatment of the disease is currently being investigated. As the metastatic ability of the cells …
treatment of the disease is currently being investigated. As the metastatic ability of the cells …