Direct compaction (DC) is the preferred choice for tablet manufacturing; however, only less
than 20% of active pharmaceutical ingredients could be compacted via DC as its high …

Fluorouracil is an anticancer drug with a short biological half-life. This study aimed to
develop oral sustained-release nano-formulations of 5-Fluorouracil. 5-Fluorouracil …

fluorouracil (FU) is an anticancer treatment with disadvantages of a short half-life and the
need for multiple intravenous administrations. The idea was to formulate oral sustained …

The aim was to develop sustained-release aqueous suspensions of ambroxol utilizing drug-
polymer complexation and raft-forming formulations. Ambroxol-carrageenan (ABX-CRG) …

Production of spherical crystals with an appropriate particle size is an important objective for
active agents dedicated to direct tablet making (Diao et al. Nat. Mater. 2011, 10, 867− 871; …

Amisulpride (AMS) is atypical antipsychotic with a weak basic nature (pKa 9.37), which
results in low solubility in the high pH of the intestine. It is also recognized as a substrate of P …

Objective: The drug will provide a therapeutic effect when dissolved so that it is easily
absorbed. The process of dissolving drugs is called dissolution. Additional substances …

Hypertension is one of the most common chronic cardiovascular disorders. Sustained-
release formulations are developed to maintain drug therapeutic levels throughout the …

The aim of any pharmaceutical dosage form designing is to formulate a product that not only
provide the desired therapeutic responses but improve patient satisfaction too. For this …

Manufacturing spherical crystals 1, 2 with appropriate particle size is an important objective
for APIs dedicated to direct tablet making. The material chosen for our experiments …