Articular cartilage (AC) has limited capacity for repair. The first attempt to repair cartilage
using tissue engineering was reported in 1977. Since then, cell-based interventions have …

Humans utilise biomineralisation in the formation of bone and teeth. Human
biomineralisation processes are defined by the transformation of an amorphous phosphate …

Tissue architecture is intimately linked with its functions, and loss of tissue organization is
often associated with pathologies. The intricate depth-dependent extracellular matrix (ECM) …

Patients with bone and cartilage defects due to infection, tumors, and trauma are quite
common. Repairing bone and cartilage defects is thus a major problem for clinicians …

The mechanical properties of the aorta are influenced by the extracellular matrix, a network
mainly comprised of fibers and glycosaminoglycans (GAG). In this work, we demonstrate that …

Here we describe a novel bioinspired hydrogel material that can be hardened with calcium
ions to yield a scaffold material with viscoelastic properties matching those of cartilage. This …

Inorganic polyphosphates (polyP) are polymers composed of phosphate residues linked by
energy‐rich phosphoanhydride bonds. As polyP can bind calcium, the hypothesis of this …

Here we describe an artificial cartilage-like material based on a hyaluronic acid-Mg/Ca-
polyphosphate paste (HA-aMg/Ca-polyP-p) that is fabricated from a water-soluble Na-salt of …

Current in vitro practices must overcome important challenges to compare favorably with
human studies. The limited applicability of conventional in vitro assays and strategies can be …

Drug delivery into articular cartilage poses many challenges due in part to its lack of
vasculature. While intra‐articular injections are effective for the local administration of drugs …