[HTML][HTML] The emerging role of cell-free DNA as a molecular marker for cancer management

AJ Bronkhorst, V Ungerer, S Holdenrieder - Biomolecular detection and …, 2019 - Elsevier
An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as a
surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …

Liquid biopsies in cancer diagnosis, monitoring, and prognosis

G De Rubis, SR Krishnan, M Bebawy - Trends in pharmacological sciences, 2019 - cell.com
Liquid biopsies, comprising the noninvasive analysis of circulating tumor-derived material
(the 'tumor circulome'), represent an innovative tool in precision oncology to overcome …

Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer

P Li, S Liu, L Du, G Mohseni, Y Zhang, C Wang - Clinical epigenetics, 2022 - Springer
Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

Salivary biomarkers for oral squamous cell carcinoma diagnosis and follow-up: current status and perspectives

M Cristaldi, R Mauceri, O Di Fede, G Giuliana… - Frontiers in …, 2019 - frontiersin.org
Oral cancer is the sixth most common cancer type in the world, and 90% of it is represented
by oral squamous cell carcinoma (OSCC). Despite progress in preventive and therapeutic …

Surface plasmon resonance for biomarker detection: advances in non-invasive cancer diagnosis

N Bellassai, R D'Agata, V Jungbluth, G Spoto - Frontiers in chemistry, 2019 - frontiersin.org
Biomarker-based cancer analysis has great potential to lead to a better understanding of
disease at the molecular level and to improve early diagnosis and monitoring. Unlike …

Microfluidics for detection of exosomes and microRNAs in cancer: State of the art

SM Mousavi, SMA Mahdian, MS Ebrahimi… - … Therapy-Nucleic Acids, 2022 - cell.com
Exosomes are small extracellular vesicles with sizes ranging from 30–150 nanometers that
contain proteins, lipids, mRNAs, microRNAs, and double-stranded DNA derived from the …

Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods

S Jordaens, K Zwaenepoel, W Tjalma… - … Journal of Cancer, 2023 - Wiley Online Library
The aim of this review was to explore the status of urine sampling as a liquid biopsy for
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …

A field guide for cancer diagnostics using cell‐free DNA: from principles to practice and clinical applications

AL Volckmar, H Sültmann, A Riediger… - Genes …, 2018 - Wiley Online Library
Recently, many genome‐wide profiling studies provided insights into the molecular make‐
up of major cancer types. The deeper understanding of these genetic alterations and their …

[HTML][HTML] Recommendations for cell-free DNA assay validations: a joint consensus recommendation of the Association for Molecular Pathology and College of …

CM Lockwood, L Borsu, M Cankovic, JSL Earle… - The Journal of molecular …, 2023 - Elsevier
Diagnosing, selecting therapy for, and monitoring cancer in patients using a minimally
invasive blood test represents a significant advance in precision medicine. Wide variability …

Liquid biopsies and cancer omics

I Amelio, R Bertolo, P Bove, OC Buonomo… - Cell Death …, 2020 - nature.com
The development of the sequencing technologies allowed the generation of huge amounts
of molecular data from a single cancer specimen, allowing the clinical oncology to enter the …