Extracellular heat shock protein 90 alpha (eHsp90α)'s role in cancer progression and the development of therapeutic strategies
TS Reynolds, BSJ Blagg - European Journal of Medicinal Chemistry, 2024 - Elsevier
Heat shock protein 90 alpha (Hsp90α) is an abundantly expressed and evolutionarily
conserved molecular chaperone. Hsp90α is the inducible Hsp90 isoform, and its expression …
conserved molecular chaperone. Hsp90α is the inducible Hsp90 isoform, and its expression …
[HTML][HTML] An update on the status of HSP90 inhibitors in cancer clinical trials
S Rastogi, A Joshi, N Sato, S Lee, JB Trepel… - Cell Stress and …, 2024 - Elsevier
The evolutionary conserved molecular chaperone HSP90 plays an indispensable role in
tumorigenesis by stabilizing client oncoproteins. Although, the functionality of HSP90 is …
tumorigenesis by stabilizing client oncoproteins. Although, the functionality of HSP90 is …
Diptoindonesin G, a new Hsp90 drug
A Wickramaratne, S Wickner - Journal of Biological Chemistry, 2023 - ASBMB
Hsp90 is a molecular chaperone that participates in protein folding, activation, and
stabilization of substrate proteins. Since many diseases, including cancer …
stabilization of substrate proteins. Since many diseases, including cancer …
C2-Arylated Indoles and Benzofurans through Formal (4 + 1) Annulation of N-Sulfonyl-2-aminobenzaldehydes and Salicylaldehyde Derivatives with Electron …
LA de Ceuninck van Capelle… - The Journal of …, 2024 - ACS Publications
A two-step formal (4+ 1) annulation-dehydration reaction offers a convenient route to C2-
arylated indoles and benzofurans. This reaction exploits the bifunctional reactivity of electron …
arylated indoles and benzofurans. This reaction exploits the bifunctional reactivity of electron …
Visualization of breast cancer-related protein synthesis from the perspective of bibliometric analysis
J Xu, C Yu, X Zeng, W Tang, S Xu, L Tang… - European Journal of …, 2023 - Springer
Breast cancer, as a daunting global health threat, has driven an exponential growth in
related research activity in recent decades. An area of research of paramount importance is …
related research activity in recent decades. An area of research of paramount importance is …
HSP90: An Emerging Molecular Target for Improvement of Nanoparticle Based Magnetic Hyperthermia Therapy
NG Shetake, A Kumar, RS Ningthoujam… - Handbook of Materials …, 2024 - Springer
Hyperthermia, as a combinatorial mode of therapy, holds a great promise to improve the
efficacy of chemo-and radiotherapy with substantial gain in the overall survival and quality of …
efficacy of chemo-and radiotherapy with substantial gain in the overall survival and quality of …
[PDF][PDF] Decrypting the role of HSP90α and β isoforms in BCR-ABL1+ leukemia and Characterization of Small Molecule HSP90 Inhibitors and Degraders
M Vogt - docserv.uni-duesseldorf.de
Despite the advancing state of medical development, as well as novel discoveries and
treatment options, cancer remains the second most common cause of death after …
treatment options, cancer remains the second most common cause of death after …