Analysis of pathogenesis and drug treatment of chronic obstructive pulmonary disease complicated with cardiovascular disease

XF Li, CQ Wan, YM Mao - Frontiers in medicine, 2022 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a disease characterized by persistent
airflow limitation, and is associated with abnormal inflammatory responses in the lungs to …

Temporal Dynamics of Cardiovascular Risk in Patients with Chronic Obstructive Pulmonary Disease During Stable Disease and Exacerbations: Review of the …

SO Simons, AB Heptinstall, Z Marjenberg… - … journal of chronic …, 2024 - Taylor & Francis
Introduction Exacerbations of chronic obstructive pulmonary disease (COPD) are risk factors
for severe cardiovascular (CV) events, with the risk remaining significantly elevated long …

Resistin as a systemic inflammation-related biomarker for sarcopenia in patients with chronic obstructive pulmonary disease

J Gao, M Deng, Y Li, Y Yin, X Zhou, Q Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Sarcopenia is common in patients with chronic obstructive pulmonary disease
(COPD) and is mainly caused by systemic inflammation. Resistin acts as a proinflammatory …

Cigarette smoke extract mediates cell premature senescence in chronic obstructive pulmonary disease patients by up-regulating USP7 to activate p300-p53/p21 …

M Zeng, X Zhang, W Xing, Q Wang, G Liang, Z He - Toxicology Letters, 2022 - Elsevier
Objectives Tobacco hazard is one of the most severe public health issues in the world. It is
believed that smoking is the most important factor leading to chronic obstructive pulmonary …

Exosomal circ-1199 derived from EPCs exposed to oscillating shear stress acts as a sponge of let-7g-5p to promote endothelial-mesenchymal transition of EPCs by …

L Li, J Wen, H Li, Y He, X Cui, X Zhang, X Guan, Z Li… - Life Sciences, 2023 - Elsevier
Aims Our previous study showed that oscillatory shear stress (OSS) induces endothelial
progenitor cells (EPCs) to undergo endothelial to mesenchymal transition (EndoMT), which …

The role of sphingolipids in regulating vascular permeability in idiopathic pulmonary fibrosis

G Jayant, S Kuperberg, K Somnay, R Wadgaonkar - Biomedicines, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a disease that causes scarring and fibrotic
transformation of the lung parenchyma, resulting in the progressive loss of respiratory …

Multidisciplinary management of patients with chronic obstructive pulmonary disease and cardiovascular disease

J de Miguel-Díez, JN Villota, SS Pérez… - Archivos de …, 2024 - Elsevier
Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD)
frequently coexist, increasing the prevalence of both entities and impacting on symptoms …

[HTML][HTML] Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress

J Wang, L Wang, X Chen, ML Liang… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
Objective (s): Cigarette smoke may play a direct role in proliferation of human pulmonary
artery smooth muscle cells (HPASMCs). However, the mechanism involved and the effect of …

LINC00599 influences smoke-related chronic obstructive pulmonary disease and regulates CSE-induced epithelial cell apoptosis and inflammation by targeting miR …

L Xu, Z Dong - Human & Experimental Toxicology, 2022 - journals.sagepub.com
LINC00599 has been reported to be upregulated in response to cigarette smoking.
However, the effect and underlying mechanism of LINC00599 in chronic obstructive …

Regulatory B cells protect against chronic hypoxia‐induced pulmonary hypertension by modulating the Tfh/Tfr immune balance

C Li, P Liu, H Yao, H Zhu, S Zhang, F Meng, S Li… - …, 2023 - Wiley Online Library
Hypoxia‐induced pulmonary hypertension (HPH) is a progressive and lethal disease
characterized by the uncontrolled proliferation of pulmonary artery smooth muscle cells …