The causative agent of melioidosis, Burkholderia pseudomallei, a tier 1 select agent, is
endemic in Southeast Asia and northern Australia, with increased incidence associated with …

Many preclinical studies in critical care medicine and related disciplines rely on hypothesis-
driven research in mice. The underlying premise posits that mice sufficiently emulate …

Burkholderia pseudomallei is a Gram-negative bacterium that infects macrophages and
other cell types and causes melioidosis. The interaction of B. pseudomallei with the …

Burkholderia pseudomallei, a facultatively intracellular pathogen, is a flagellated and motile
gram-negative bacterium and is the causative agent of melioidosis in humans. Flagella are …

Certain environmental microorganisms can cause severe human infections, even in the
absence of an obvious requirement for transition through an animal host for replication …

Inhalation is an important route of infection with Burkholderia pseudomallei the causative
agent of melioidosis. In resistant C57BL/6 mice, activated neutrophils are rapidly recruited to …

Individuals with type 2 diabetes are at increased risk of acquiring melioidosis, a disease
caused by Burkholderia pseudomallei infection. Although up to half of melioidosis patients …

The Burkholderia pseudomallei K96243 genome contains multiple type IV pilin-associated
loci, including one encoding a putative pilus structural protein (pilA). A pilA deletion mutant …

Burkholderia pseudomallei is the causative agent for melioidosis, an infectious disease
endemic in South‐east Asia and northern Australia. Infection can result in a wide spectrum …

Burkholderia pseudomallei is a gram-negative bacterium that is the etiological agent of the
tropical disease melioidosis. Currently, there is no licensed vaccine for melioidosis, but …