Vascular organoids: unveiling advantages, applications, challenges, and disease modelling strategies

H Naderi-Meshkin, VA Cornelius… - Stem Cell Research & …, 2023 - Springer
Understanding mechanisms and manifestations of cardiovascular risk factors, including
diabetes, on vascular cells such as endothelial cells, pericytes, and vascular smooth muscle …

Lymphatic vessel: origin, heterogeneity, biological functions, and therapeutic targets

Z Hu, X Zhao, Z Wu, B Qu, M Yuan, Y Xing… - … and Targeted Therapy, 2024 - nature.com
Lymphatic vessels, comprising the secondary circulatory system in human body, play a
multifaceted role in maintaining homeostasis among various tissues and organs. They are …

The lymphatic vascular system: much more than just a sewer

J Wilting, J Becker - Cell & Bioscience, 2022 - Springer
Almost 400 years after the (re) discovery of the lymphatic vascular system (LVS) by Gaspare
Aselli (Asellius G. De lactibus, sive lacteis venis, quarto vasorum mesaraicorum genere …

Lymphatic/blood vessel plasticity: motivation for a future research area based on present and past observations

AO Lampejo, SAA Ghavimi… - American Journal …, 2023 - journals.physiology.org
The lymphatic system plays a significant role in homeostasis and drainage of excess fluid
back into venous circulation. Lymphatics are also associated with a number of diseases …

The relationship between the secondary vascular system and the lymphatic vascular system in fish

V Panara, Z Varaliová, J Wilting, K Koltowska… - Biological …, 2024 - Wiley Online Library
New technologies have resulted in a better understanding of blood and lymphatic vascular
heterogeneity at the cellular and molecular levels. However, we still need to learn more …

Revealing the role of zinc ions in atherosclerosis therapy via an engineered three‐dimensional pathological model

Y Wang, N Huang, Z Yang - Advanced Science, 2023 - Wiley Online Library
An incomplete understanding of the cellular functions and underlying mechanisms of zinc
ions released from zinc‐based stents in atherosclerosis (AS) therapy is one of the major …

Lymphatic vasculature in the central nervous system

S González-Hernández, Y Mukouyama - Frontiers in Cell and …, 2023 - frontiersin.org
The central nervous system (CNS) is considered as an immune privilege organ, based on
experiments in the mid 20th century showing that the brain fails to mount an efficient immune …

egr3 is a mechanosensitive transcription factor gene required for cardiac valve morphogenesis

AR da Silva, F Gunawan, GLM Boezio, E Faure… - Science …, 2024 - science.org
Biomechanical forces, and their molecular transducers, including key mechanosensitive
transcription factor genes, such as KLF2, are required for cardiac valve morphogenesis …

Mechanical forces in lymphatic vessel development: Focus on transcriptional regulation

N Ujiie, T Kume - Frontiers in Physiology, 2022 - frontiersin.org
The lymphatic system is crucial for the maintenance of interstitial fluid and protein
homeostasis. It has important roles in collecting excess plasma and interstitial fluid leaked …

Expansion and collapse of VEGF diversity in major clades of the animal kingdom

K Rauniyar, H Bokharaie, M Jeltsch - Angiogenesis, 2023 - Springer
Together with the platelet-derived growth factors (PDGFs), the vascular endothelial growth
factors (VEGFs) form the PDGF/VEGF subgroup among cystine knot growth factors. The …