Adipose tissue depots can exist in close association with other organs, where they assume
diverse, often non-traditional functions. In stem cell-rich skin, bone marrow, and mammary …

This article reviews the mechanisms that lead to the development of Graves'
ophthalmopathy. A central feature in its development is autoimmunity that involves not only T …

This review focuses on the contribution of white, brown, and perivascular adipose tissues to
the pathophysiology of obesity and its associated metabolic and vascular complications …

Arachidonic acid (AA)-derived eicosanoids belong to a complex family of lipid mediators that
regulate a wide variety of physiological responses and pathological processes. They are …

Graves' disease (GD) is a common autoimmune condition. At its core, stimulatory
autoantibodies are directed at the thyroid-stimulating hormone receptor (TSHR), resulting in …

Graves' ophthalmopathy (GO) is an extra-thyroidal complication of Graves' disease (GD;
Graves' hyperthyroidism) characterized by orbital tissue inflammation, expansion …

Elucidation of the periosteum and its regenerative potential has become a hot topic in
orthopedics. Yet few review articles address the unique features of periosteum-derived cells …

Eicosanoids are inflammatory mediators primarily generated by hydrolysis of membrane
phospholipids by phospholipase A2 to ω-3 and ω-6 C20 fatty acids that next are converted …

Thyroid eye disease (TED) is an inflammatory condition of the orbit closely associated with
Graves' disease. During the course of TED, fibrosis can develop around the extraocular …

The body's autoimmune process is involved in the development of Graves' disease (GD),
which is manifested by an overactive thyroid gland. In some patients, autoreactive …