In the inner ear, sensory hair cells not only detect but also amplify the softest sounds,
allowing us to hear over an extraordinarily wide intensity range. This amplification is …

Hair cells (HCs) are specialised sensory receptors residing in the neurosensory epithelia of
inner ear sense organs. The precise morphological and physiological properties of HCs …

Gross‐potential recordings in mice lacking the Prestin gene indicate that compound action
potential (CAP) thresholds are shifted by∼ 45 dB at 5 kHz and by∼ 60 dB at 33 kHz …

The development of therapeutic interventions for hearing loss requires fundamental
knowledge about the signaling pathways controlling tissue development as well as the …

More than 6% of the world's population is suffering from hearing loss and balance disorders.
The inner ear is the organ that senses sound and balance. Although inner ear disorders are …

Prestin is the motor protein responsible for the somatic electromotility of cochlear outer hair
cells and is essential for normal hearing sensitivity and frequency selectivity of mammals …

There is a huge potential market for the treatment of hearing loss. Drugs are already
available to ameliorate predictable, damaging effects of excessive noise and ototoxic drugs …

In this paper we present a sound-source model for localising and tracking an acoustic
source of interest along the azimuth plane in acoustically cluttered environments, for a …

Prestin is a transmembrane motor protein localized at the outer hair cells (OHCs) of the
mammalian inner ear. Voltage-dependent conformational changes in prestin generate …

This chapter provides an overview of the first auditory synapses, in the cochlea where sound
is encoded. We review insights into the development, structure, and function of the excitatory …