The discovery of regulated cell death processes has enabled advances in cancer treatment.
In the past decade, ferroptosis, an iron-dependent form of regulated cell death driven by …

Metastasis formation is the major cause of death in most patients with cancer. Despite
extensive research, targeting metastatic seeding and colonization is still an unresolved …

Ferroptosis is an iron-dependent and lipid peroxidation-driven cell death cascade, occurring
when there is an imbalance of redox homeostasis in the cell. Nuclear factor erythroid 2 …

Background & Aims Squalene epoxidase (SQLE), a rate-limiting enzyme in cholesterol
biosynthesis, is suggested as a proto-oncogene. Paradoxically, SQLE is degraded by …

Background Recently, the preoperative immune-nutritional status has been reported to
correlate with the survival rate in patients with colorectal cancer (CRC). However, there have …

Lipid metabolism disorder is related to an increased risk of tumorigenesis and is involved in
the rapid growth of cancer cells as well as the formation of metastatic lesions …

Background The prevalence of dyslipidemia in patients with type 2 diabetes (T2D) has been
reported to be relatively high. The current study aimed to investigate the trend of serum lipid …

AIM: To investigate the correlations between lipid metabolism disorder and the occurrence
and development of colorectal cancer by monitoring the alterations in lipid levels in …

Background: The purpose of this study was to determine if pretreatment serum albumin and
cholesterol levels are prognostic factors in patients with colorectal carcinomas …

Colorectal cancer (CRC) is a highly prevalent malignancy with multifactorial etiology, which
includes metabolic alterations as contributors to disease development. Studies have shown …