[HTML][HTML] Targeting the organelle for radiosensitization in cancer radiotherapy

X Sun, L Wu, L Du, W Xu, M Han - Asian Journal of Pharmaceutical …, 2024 - Elsevier
Radiotherapy is a well-established cytotoxic therapy for local solid cancers, utilizing high-
energy ionizing radiation to destroy cancer cells. However, this method has several …

Synthesis and Preclinical Evaluation of PSMA-Targeted 111In-Radioconjugates Containing a Mitochondria-Tropic Triphenylphosphonium Carrier

JF Santos, MT Braz, P Raposinho… - Molecular …, 2023 - ACS Publications
Nuclear DNA is the canonical target for biological damage induced by Auger electrons (AE)
in the context of targeted radionuclide therapy (TRT) of cancer, but other subcellular …

CIB2 as a Ca2+ Sensor for Auditory Mechano-Electrical Transduction and Linked to Genetic-Heterogeneity of TMC1 in Hearing Loss

S Wu, L Lin, Q Hu, X Yao, H Wang, S Liu, Q Liu, Y Xi… - bioRxiv, 2024 - biorxiv.org
Non-syndromic sensorineural hearing loss is characterized by genetic heterogeneity,
leading to potential clinical misdiagnosis. TMC1, a unique causative gene associated with …