Primary lymphoedema

P Brouillard, MH Witte, RP Erickson… - Nature reviews Disease …, 2021 - nature.com
Lymphoedema is the swelling of one or several parts of the body owing to lymph
accumulation in the extracellular space. It is often chronic, worsens if untreated, predisposes …

Understanding lymphatic anatomy and abnormalities at imaging

E Lee, DM Biko, W Sherk, WR Masch… - Radiographics, 2022 - pubs.rsna.org
Lymphatic abnormalities encompass a wide range of disorders spanning solitary common
cystic lymphatic malformations (LMs) to entities involving multiple organ systems such as …

Severe lymphatic disorder resolved with MEK inhibition in a patient with Noonan syndrome and SOS1 mutation

Y Dori, C Smith, E Pinto, K Snyder, ME March… - …, 2020 - publications.aap.org
Noonan syndrome is a multiorgan system disorder mediated by genetic defects along the rat
sarcoma–mitogen-activated protein kinase (RAS-MAPK) pathway known as RASopathies. It …

Surgical management of central lymphatic conduction disorders: a review

P Laje, Y Dori, C Smith, E Pinto, D Taha… - Journal of Pediatric …, 2024 - Elsevier
Aim Recent advances in lymphatic imaging allow understanding the pathophysiology of
lymphatic central conduction disorders with great accuracy. This new imaging data is …

MRI of lymphedema

BP Salehi, RC Sibley, R Friedman… - Journal of Magnetic …, 2023 - Wiley Online Library
Lymphedema is a devastating disease that has no cure. Management of lymphedema has
evolved rapidly over the past two decades with the advent of surgeries that can ameliorate …

Lymphatic disorders in patients with single ventricle heart disease

Y Dori, CL Smith - Frontiers in Pediatrics, 2022 - frontiersin.org
Lymphatic abnormalities in patients with single ventricle physiology can lead to early Fontan
failure and severe Fontan complications, such as protein-losing enteropathy (PLE), plastic …

Dynamic contrast-enhanced magnetic resonance lymphangiography

KI Ramirez-Suarez, LO Tierradentro-Garcia… - Pediatric …, 2022 - Springer
Lymphatic flow disorders include a broad spectrum of abnormalities that can originate in the
lymphatic or the venous system. The development of these disorders is multifactorial and is …

MR lymphangiography in lymphatic disorders: clinical applications, institutional experience, and practice development

AS Negm, JD Collins, EC Bendel, E Takahashi… - …, 2024 - pubs.rsna.org
Lymphatic flow and anatomy can be challenging to study, owing to variable lymphatic
anatomy in patients with diverse primary or secondary lymphatic pathologic conditions and …

Intramesenteric dynamic contrast pediatric MR lymphangiography: initial experience and comparison with intranodal and intrahepatic MR lymphangiography

Y Dori, CL Smith, AG DeWitt, A Srinivasan… - European …, 2020 - Springer
Objectives To report on our initial experience with intramesenteric (IM) dynamic contrast
magnetic resonance lymphangiography (DCMRL) for evaluation of the lymphatics in …

Decompression of the thoracic duct: a novel transcatheter approach

CL Smith, TM Hoffman, Y Dori… - Catheterization and …, 2020 - Wiley Online Library
In patients with total cavopulmonary connections, elevated central venous pressures (CVP)
have detrimental effects on the lymphatic system causing an imbalance in fluid production …