Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …

Understanding and controlling the spread of antimalarial resistance, particularly to
artemisinin and its partner drugs, is a top priority. Plasmodium falciparum parasites resistant …

The mechanism of action of artemisinin and its derivatives, the most potent of the anti-
malarial drugs, is not completely understood. Here we present an unbiased chemical …

Plasmodium falciparum resistance to artemisinin derivatives in southeast Asia threatens
malaria control and elimination activities worldwide. To monitor the spread of artemisinin …

Artemisinins are the cornerstone of anti-malarial drugs. Emergence and spread of resistance
to them,, raises risk of wiping out recent gains achieved in reducing worldwide malaria …

Artemisinin and its derivatives (collectively referred to as ARTs) rapidly reduce the parasite
burden in Plasmodium falciparum infections, and antimalarial control is highly dependent on …

Artemisinin partial resistance may facilitate selection of Plasmodium falciparum resistant to
combination therapy partner drugs. We evaluated 99 P. falciparum isolates collected in 2021 …

The worldwide use of artemisinin-based combination therapies (ACTs) has contributed in
recent years to a substantial reduction in deaths resulting from Plasmodium falciparum …

The field of Traditional Chinese Medicine (TCM) represents a vast and largely untapped
resource for modern medicine. Exemplified by the success of the antimalarial artemisinin …

Malaria, mostly due to Plasmodium falciparum infection in Africa, remains one of the most
important infectious diseases in the world. Standard treatment for uncomplicated P …