Inflammation: the driver of poor outcomes among children with severe acute malnutrition?

JP Sturgeon, JM Njunge, CD Bourke… - Nutrition …, 2023 - academic.oup.com
Severe acute malnutrition (SAM) is the most life-threatening form of undernutrition and
underlies at least 10% of all deaths among children younger than 5 years in low-income …

Campylobacter vaccination reduces diarrheal disease and infant growth stunting among rhesus macaques

SM Hendrickson, A Thomas, HP Raué… - Nature …, 2023 - nature.com
Campylobacter-associated enteric disease is estimated to be responsible for more than 160
million cases of gastroenteritis each year and is linked to growth stunting of infants living …

Is there dietary macronutrient malabsorption in children with environmental enteropathy?

N Shivakumar, DJ Morrison, SG Hegde… - European journal of …, 2024 - nature.com
Assessing the digestive and absorptive capacity of the gastro-intestinal tract (GIT) using
minimally-or non-invasive methods, particularly in children, has been difficult owing to the …

Immunogenicity and safety of an Entamoeba histolytica adjuvanted protein vaccine candidate (LecA+GLA-3M-052 liposomes) in rhesus macaques

MM Abhyankar, F Xu, D Chavez… - Human Vaccines & …, 2024 - Taylor & Francis
Entamoeba histolytica, the causative agent of amebiasis, is one of the top three parasitic
causes of mortality worldwide. However, no vaccine exists against amebiasis. Using a lead …

Infant diarrheal disease in rhesus macaques impedes microbiome maturation and is linked to uncultured Campylobacter species

NS Rhoades, IR Cinco, SM Hendrickson… - Communications …, 2024 - nature.com
Diarrheal diseases remain one of the leading causes of death for children under 5 globally,
disproportionately impacting those living in low-and middle-income countries (LMIC) …

Maintenance of caecal homeostasis by diverse adaptive immune cells in the rhesus macaque

X Castro Dopico, M Guryleva… - Clinical & …, 2024 - Wiley Online Library
Objectives The caecum bridges the small and large intestine and plays a front‐line role in
discriminating gastrointestinal antigens. Although dysregulated in acute and chronic …

[HTML][HTML] A cross-sectional study of associations between the 13C-sucrose breath test, the lactulose rhamnose assay, and growth in children at high risk of …

N Shivakumar, S Huq, M Paredes-Olortegui… - The American Journal of …, 2024 - Elsevier
Background Environmental enteropathy'(EE) is common among children who are highly
exposed to enteric pathogens in low-resource settings. We optimized and validated a stable …

Evidence of potential Campylobacter jejuni zooanthroponosis in captive macaque populations

X Zang, B Pascoe, E Mourkas, K Kong… - Microbial …, 2023 - microbiologyresearch.org
Non-human primates share recent common ancestry with humans and exhibit comparable
disease symptoms. Here, we explored the transmission potential of enteric bacterial …

Protein status in relation to linear growth faltering and environmental enteropathy

N Shivakumar, P Kelly - Current Opinion in Clinical Nutrition & …, 2024 - journals.lww.com
Protein status in relation to linear growth faltering and en... : Current Opinion in Clinical
Nutrition & Metabolic Care Protein status in relation to linear growth faltering and …

Infant diarrheal disease impedes maturation of the microbiome and is linked to a diverse set of novel yet to be cultured Campylobacter species.

I Messaoudi, N Rhoades, I Cinco, S Hendrickson… - 2023 - researchsquare.com
Diarrheal diseases remain one of the leading causes of death for children under 5 globally,
disproportionately impacting those living in low-and middle-income countries (LMIC) …