Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons–a scoping review

H Bliddal, AR Leeds, R Christensen - Obesity reviews, 2014 - Wiley Online Library
Obesity is widely acknowledged as a risk factor for both the incidence and progression of
osteoarthritis, and has a negative influence on outcomes. Loss of at least 10% of body …

Epidemiology of OA

T Neogi, Y Zhang - Rheumatic diseases clinics of North …, 2012 - pmc.ncbi.nlm.nih.gov
Osteoarthritis (OA) is the most common form of arthritis in the US, and a leading cause of
disability. It is typically defined in epidemiologic studies on the basis of radiographic findings …

Association between overweight and obesity and risk of clinically diagnosed knee, hip, and hand osteoarthritis: a population‐based cohort study

C Reyes, KM Leyland, G Peat, C Cooper… - Arthritis & …, 2016 - Wiley Online Library
Objective Studies of previous cohorts have demonstrated an association between a status of
overweight/obesity and the presence of knee and hand osteoarthritis (OA). However, no …

A causal relationship between childhood obesity and risk of osteoarthritis: results from a two-sample Mendelian randomization analysis

Z Cao, Y Wu, Q Li, Y Li, J Wu - Annals of medicine, 2022 - Taylor & Francis
Purpose It has been found that childhood obesity (CO) may play an important role in the
onset and progression of osteoarthritis (OA). Thus we conducted this mendelian …

Estimating the burden of total knee replacement in the United States

AM Weinstein, BN Rome, WM Reichmann, JE Collins… - JBJS, 2013 - journals.lww.com
Background: In the last decade, the number of total knee replacements performed annually
in the United States has doubled, with disproportionate increases among younger adults …

Prevalence of abnormalities in knees detected by MRI in adults without knee osteoarthritis: population based observational study (Framingham Osteoarthritis Study)

A Guermazi, J Niu, D Hayashi, FW Roemer, M Englund… - Bmj, 2012 - bmj.com
Objective To examine use of magnetic resonance imaging (MRI) of knees with no
radiographic evidence of osteoarthritis to determine the prevalence of structural lesions …

[HTML][HTML] Fundamentals of OA. An initiative of Osteoarthritis and Cartilage. Obesity and metabolic factors in OA

A Batushansky, S Zhu, RK Komaravolu, S South… - Osteoarthritis and …, 2022 - Elsevier
Objective Obesity was once considered a risk factor for knee osteoarthritis (OA) primarily for
biomechanical reasons. Here we provide an additional perspective by discussing how …

Osteoarthritis prevalence and modifiable factors: a population study

R Plotnikoff, N Karunamuni, E Lytvyak, C Penfold… - BMC public health, 2015 - Springer
Background This study's objectives were to investigate the prevalence of self-reported knee
and hip osteoarthritis (OA) stratified by age and sex and to examine the association of …

How has the age-related process of overweight or obesity development changed over time? Co-ordinated analyses of individual participant data from five United …

W Johnson, L Li, D Kuh, R Hardy - PLoS medicine, 2015 - journals.plos.org
Background There is a paucity of information on secular trends in the age-related process by
which people develop overweight or obesity. Utilizing longitudinal data in the United …

[PDF][PDF] Consideration of the evidence on childhood obesity for the Commission on Ending Childhood Obesity: report of the ad hoc working group on science and …

World Health Organization - 2016 - apps.who.int
6. INTERVENTIONS TO ADDRESS CHILDHOOD OBESITY 6.1. Preconception and
pregnancy: reducing obesity risk 6.2. Obesity prevention in infants, preschool children …