Small molecule metabolites: discovery of biomarkers and therapeutic targets

S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

[HTML][HTML] Unlocking tomorrow's health care: Expanding the clinical scope of wearables by applying artificial intelligence

TB Marvasti, Y Gao, KR Murray, S Hershman… - Canadian Journal of …, 2024 - Elsevier
As an integral aspect of healthcare, digital technology has enabled modeling of complex
relationships to detect, screen, diagnose and predict patient outcomes. With massive …

Recent developments in machine learning modeling methods for hypertension treatment

H Kohjitani, H Koshimizu, K Nakamura… - Hypertension …, 2024 - nature.com
Hypertension is the leading cause of cardiovascular complications. This review focuses on
the advancements in medical artificial intelligence (AI) models aimed at individualized …

Exploring machine learning strategies for predicting cardiovascular disease risk factors from multi-omic data

G Drouard, J Mykkänen, J Heiskanen… - BMC Medical Informatics …, 2024 - Springer
Background Machine learning (ML) classifiers are increasingly used for predicting
cardiovascular disease (CVD) and related risk factors using omics data, although these …

Individualized treatment decision model for inoperable elderly esophageal squamous cell carcinoma based on multi-modal data fusion

Y Huang, X Huang, A Wang, Q Chen, G Chen… - BMC Medical Informatics …, 2023 - Springer
Background This research aimed to develop a model for individualized treatment decision-
making in inoperable elderly patients with esophageal squamous cell carcinoma (ESCC) …

[HTML][HTML] Integrating genetics, metabolites, and clinical characteristics in predicting cardiometabolic health outcomes using machine learning algorithms–A systematic …

X Zhu, EF Ventura, S Bansal, A Wijeyesekera… - Computers in biology …, 2025 - Elsevier
Background Machine learning (ML) integration of clinical, metabolite, and genetic data
reveals variable results in predicting cardiometabolic health (CMH) outcomes. Therefore, we …

Application of artificial intelligence in hypertension

JS Cho, JH Park - Clinical Hypertension, 2024 - Springer
Hypertension is an important modifiable risk factor for morbidity and mortality associated
with cardiovascular disease. The incidence of hypertension is increasing not only in Korea …

Combating hypertension beyond genome-wide association studies: Microbiome and artificial intelligence as opportunities for precision medicine

S Aryal, I Manandhar, X Mei, BS Yeoh… - Cambridge Prisms …, 2023 - cambridge.org
The single largest contributor to human mortality is cardiovascular disease, the top risk factor
for which is hypertension (HTN). The last two decades have placed much emphasis on the …

Unraveling phenotypic variance in metabolic syndrome through multi-omics

LD Amente, NT Mills, TD Le, E Hyppönen, SH Lee - Human Genetics, 2024 - Springer
Complex multi-omics effects drive the clustering of cardiometabolic risk factors, underscoring
the imperative to comprehend how individual and combined omics shape phenotypic …

[HTML][HTML] DeepForest-HTP: A novel deep forest approach for predicting antihypertensive peptides

Q Bai, H Chen, W Li, L Li, J Li, Z Gao, Y Li, X Li… - Computer Methods and …, 2025 - Elsevier
Hypertension is a major preventable risk factor for cardiovascular disease, affecting over 1.5
billion adults worldwide. Antihypertensive peptides (AHTPs) have gained attention as a …