The ability of Salmonella to form complex surface-associated communities, called biofilms,
contributes to its resistance and persistence in both host and non-host environments and is …

Escherichia coli is equipped with multiple systems to ensure safe copper handling under
varying environmental conditions. The Cu (I)-translocating P-type ATPase CopA, the central …

The Gram-negative bacterial envelope is an essential interface between the intracellular
and harsh extracellular environment. Envelope stress responses (ESRs) are crucial to the …

▪ Abstract The promoter recognition specificity of Escherichia coli RNA polymerase is
modulated by replacement of the σ subunit in the first step and by interaction with …

Bacteria possess a signal transduction system, referred to as a two-component system, for
adaptation to external stimuli. Each two-component system consists of a sensor protein …

ABSTRACT The Escherichia coli OmpR/EnvZ two-component regulatory system, which
senses environmental osmolarity, also regulates biofilm formation. Up mutations in the …

Because copper catalyzes the conversion of H2O2 to hydroxyl radicals in vitro, it has been
proposed that oxidative DNA damage may be an important component of copper toxicity …

Because copper ions are both essential cofactors and cytotoxic agents, the net accumulation
of this element in a cell must be carefully balanced. Depending upon the cellular copper …

The Cpx envelope stress response (ESR) has been linked to proteins that are integrated into
and secreted across the inner membrane for several decades. Initial studies of the cpx locus …

We have systematically examined the mRNA profiles of 36 two‐component deletion
mutants, which include all two‐component regulatory systems of Escherichia coli, under a …