Brain connectomics: time for a molecular imaging perspective?

A Sala, A Lizarraga, SP Caminiti, VD Calhoun… - Trends in cognitive …, 2023 - cell.com
In the past two decades brain connectomics has evolved into a major concept in
neuroscience. However, the current perspective on brain connectivity and how it underpins …

The metabolic costs of cognition

SD Jamadar, A Behler, H Deery… - Trends in Cognitive …, 2025 - cell.com
Cognition and behavior are emergent properties of brain systems that seek to maximize
complex and adaptive behaviors while minimizing energy utilization. Different species …

Integrating multimodal and multiscale connectivity blueprints of the human cerebral cortex in health and disease

JY Hansen, G Shafiei, K Voigt, EX Liang, SML Cox… - PLoS …, 2023 - journals.plos.org
The brain is composed of disparate neural populations that communicate and interact with
one another. Although fiber bundles, similarities in molecular architecture, and synchronized …

Reconfiguration of metabolic connectivity in ageing

HA Deery, EX Liang, MN Siddiqui, G Murray… - Communications …, 2024 - nature.com
Abstract Information transfer across the brain has a high energetic cost and requires efficient
glucose metabolism. Here we use recently developed high temporal resolution functional …

Spatiotemporal topological correspondence between blood oxygenation and glucose metabolism revealed by simultaneous fPET-fMRI in brain's white matter

J Li, GR Wu, M Shi, J Xia, Y Meng, S Yang… - Cerebral …, 2023 - academic.oup.com
White matter (WM) makes up half of the human brain. Compelling functional MRI evidence
indicates that white matter exhibits neural activation and synchronization via a …

Dialogue mechanisms between astrocytic and neuronal networks: A whole-brain modelling approach

OBK Ali, A Vidal, C Grova, H Benali - PLOS Computational Biology, 2025 - journals.plos.org
Astrocytes critically shape whole-brain structure and function by forming extensive gap
junctional networks that intimately and actively interact with neurons. Despite their …

Persistent dysfunctions of brain metabolic connectivity in long-covid with cognitive symptoms

AL Martini, G Carli, SP Caminiti, L Kiferle, A Leo… - European Journal of …, 2024 - Springer
Purpose Our study examines brain metabolic connectivity in SARS-CoV-2 survivors during
the acute-subacute and chronic phases, aiming to elucidate the mechanisms underlying the …

Benchmarking methods for mapping functional connectivity in the brain

ZQ Liu, AI Luppi, JY Hansen, YE Tian, A Zalesky… - bioRxiv, 2024 - biorxiv.org
The networked architecture of the brain promotes synchrony among neuronal populations
and the emergence of coherent dynamics. These communication patterns can be …

Mechanisms underlying delirium in patients with critical illness

YY Fan, RY Luo, MT Wang, CY Yuan… - Frontiers in Aging …, 2024 - frontiersin.org
Delirium is an acute, global cognitive disorder syndrome, also known as acute brain
syndrome, characterized by disturbance of attention and awareness and fluctuation of …

PET-based brain molecular connectivity in neurodegenerative disease

JU Hanania, E Reimers, CWJ Bevington… - Current Opinion in …, 2024 - journals.lww.com
Connectivity approaches are poised to greatly enhance the information that can be extracted
from molecular imaging. While currently mostly contributing to enhancing understanding of …