Hypericin-mediated photodynamic therapy for the treatment of cancer: a review

X Dong, Y Zeng, Z Zhang, J Fu, L You… - Journal of Pharmacy …, 2021 - academic.oup.com
Objectives Hypericin is a polycyclic aromatic naphthodianthrone that occurs naturally. It is
also an active ingredient in some species of the genus Hypericum. Emerging evidence …

Enhancement of anti-tumor immunity by photodynamic therapy

SO Gollnick, CM Brackett - Immunologic research, 2010 - Springer
Photodynamic therapy (PDT) is an FDA-approved modality that rapidly eliminates local
tumors, resulting in cure of early disease and palliation of advanced disease. PDT was …

[图书][B] CRC Handbook of Organic Photochemistry and Photobiology, Volumes 1 & 2

WM Horspool, F Lenci - 2003 - taylorfrancis.com
The second edition of this best-selling handbook is bigger, more comprehensive, and now
completely current. In addition to thorough updates to the discussions featured in the first …

Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically …

K Hostanska, J Reichling, S Bommer, M Weber… - European Journal of …, 2003 - Elsevier
Hyperforin (HP) is an abundant component of St John's wort with antibiotic and
antidepressive activity. We report here the ability of HP and that of polyphenolic procyanidin …

The immunological consequences of photodynamic treatment of cancer, a literature review

FH van Duijnhoven, RIJM Aalbers, JP Rovers… - Immunobiology, 2003 - Elsevier
In this review we discuss the effect of photodynamic treatment (PDT) of solid tumors on the
immune response. The effect on both the innate and adapted immune response is …

CD8+ T cell-mediated control of distant tumours following local photodynamic therapy is independent of CD4+ T cells and dependent on natural killer cells

E Kabingu, L Vaughan, B Owczarczak… - British journal of …, 2007 - nature.com
Cancer survival rates decrease in the presence of disseminated disease. However, there
are few therapies that are effective at eliminating the primary tumour while providing control …

Development of photodynamic therapy regimens that control primary tumor growth and inhibit secondary disease

M Shams, B Owczarczak, P Manderscheid-Kern… - Cancer Immunology …, 2015 - Springer
Effective therapy for advanced cancer often requires treatment of both primary tumors and
systemic disease that may not be apparent at initial diagnosis. Numerous studies have …

Changes in essential oil composition in Saint John's wort (Hypericum perforatum L.) aerial parts during its phenological cycle

I Schwob, JM Bessiere, V Masotti, J Viano - Biochemical systematics and …, 2004 - Elsevier
The quantitative and qualitative variations of the essential oil from the aerial parts of
Hypericum perforatum were examined. Plant material was harvested at different …

Animal models for photodynamic therapy (PDT)

ZS Silva Jr, SK Bussadori, KPS Fernandes… - Bioscience …, 2015 - portlandpress.com
Photodynamic therapy (PDT) employs non-toxic dyes called photosensitizers (PSs), which
absorb visible light to give the excited singlet state, followed by the long-lived triplet state …

Low dose hypericin-PDT induces complete tumor regression in BALB/c mice bearing CT26 colon carcinoma

R Sanovic, T Verwanger, A Hartl, B Krammer - … and photodynamic therapy, 2011 - Elsevier
BACKGROUND: Successful tumor eradication with photodynamic therapy (PDT) in vivo
depends on the optimal combination of treatment parameters.(Low-dose) PDT may …