Chronic lung allograft dysfunction (CLAD) is the major limitation of long-term survival after
lung transplantation. Chronic lung allograft dysfunction manifests as bronchiolitis obliterans …

Since the inception of lung transplantation (LTx), serial pulmonary function testing (PFT) has
been the primary method of quantifying the physiologic performance of the allograft. The …

Chronic lung allograft dysfunction (CLAD) remains the major barrier to long‐term survival
after lung transplantation and improved insight into its underlying immunological …

Rationale: Frailty is associated with morbidity and mortality in abdominal organ
transplantation but has not been examined in lung transplantation. Objectives: To examine …

Abstract Machine perfusion is a hot topic in liver transplantation and several new perfusion
concepts are currently developed. Prior to introduction into routine clinical practice, however …

Chronic lung allograft dysfunction (CLAD) remains a frequent and troublesome complication
after lung transplantation. Apart from bronchiolitis obliterans syndrome (BOS), a restrictive …

Lung transplantation has developed significantly in recent years, but post-transplant care
and patients' survival still need to be improved. Moreover, organ shortage urges novel …

OBJECTIVES: Availability of donor lungs suitable for transplant falls short of current demand
and contributes to waiting list mortality. Ex vivo lung perfusion (EVLP) offers the opportunity …

Genetic modification therapy is a promising therapeutic strategy for many diseases of the
lung intractable to other treatments. Lung gene therapy has been the subject of numerous …

Background Although the benefits of ex vivo lung perfusion (EVLP) have been globally
advocated, the potentially deleterious effects of applying EVLP, in particular activation of …