Chronically implanted recording electrode arrays linked to prosthetics have the potential to
make positive impacts on patients suffering from full or partial paralysis. Such arrays are …

Since the original demonstration that electrical activity generated by ensembles of cortical
neurons can be employed directly to control a robotic manipulator, research on brain …

Owing to its superior tribological and mechanical properties with corrosion resistance,
biocompatibility, and hemocompatibility, diamond-like carbon (DLC) has emerged as a …

Chronic recordings from micromachined neural electrode arrays often fail a few weeks after
implantation primarily due to the formation of an astro-glial sheath around the implant. We …

Amorphous hydrogenated diamond-like carbon (DLC) and tetrahedral carbon (taC) films are
characterized by high wear resistance, low friction coefficients and chemical inertness, thus …

Neuroscientists have long recognized the importance of understanding the underlying
principles of information processing by large populations of neurons. Methods for Neural …

Despite enormous advances made in the development of external effector prosthetics over
the last quarter century, significant questions remain, especially those concerning signal …

The ability to culture cells in vitro has revolutionized hypothesis testing in basic cell and
molecular biology research and has become a standard methodology in drug screening and …

Chemical surface modification of neuron-surface interfaces is essential for the development
of biologically active and functional neural interfaces. Different types of surface modification …

Alzheimer's disease (AD) is the most common cause of dementia in the elderly, clinically
defined by progressive cognitive decline and pathologically, by brain atrophy …