Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …
personalized approaches to cancer treatment are on the rise. For example, targeted drug …
Nanoparticle-mediated cancer cell therapy: Basic science to clinical applications
Every sixth person in the world dies due to cancer, making it the second leading severe
cause of death after cardiovascular diseases. According to WHO, cancer claimed nearly 10 …
cause of death after cardiovascular diseases. According to WHO, cancer claimed nearly 10 …
An updated review on EPR-based solid tumor targeting nanocarriers for cancer treatment
Simple Summary One of the important efforts in the treatment of cancers is to achieve
targeted drug delivery by nanocarriers to be more effective and reduce adverse effects …
targeted drug delivery by nanocarriers to be more effective and reduce adverse effects …
Nexus between in silico and in vivo models to enhance clinical translation of nanomedicine
In cancer, one of the main barriers to effective chemotherapy is inefficient drug delivery. The
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
Ultrasound‐mediated nano‐sized drug delivery systems for cancer treatment: Multi‐scale and multi‐physics computational modeling
F Moradi Kashkooli, TK Hornsby… - Wiley …, 2024 - Wiley Online Library
Computational modeling enables researchers to study and understand various complex
biological phenomena in anticancer drug delivery systems (DDSs), especially nano‐sized …
biological phenomena in anticancer drug delivery systems (DDSs), especially nano‐sized …
Interstitial fluid pressure as an emerging biomarker in solid tumors
The physical microenvironment of cancer is characterized by elevated stiffness and tissue
pressure, the main component of which is the interstitial fluid pressure (IFP). Elevated IFP is …
pressure, the main component of which is the interstitial fluid pressure (IFP). Elevated IFP is …
In silico modelling of cancer nanomedicine, across scales and transport barriers
Nanoparticles promise to improve the treatment of cancer through their increasingly
sophisticated functionalisations and ability to accumulate in certain tumours. Yet recent work …
sophisticated functionalisations and ability to accumulate in certain tumours. Yet recent work …
Enhanced drug delivery to solid tumors via drug-loaded nanocarriers: An image-based computational framework
F Moradi Kashkooli, M Soltani, MM Momeni… - Frontiers in …, 2021 - frontiersin.org
Objective Nano-sized drug delivery systems (NSDDSs) offer a promising therapeutic
technology with sufficient biocompatibility, stability, and drug-loading rates towards efficient …
technology with sufficient biocompatibility, stability, and drug-loading rates towards efficient …
Computational fluid dynamics with imaging of cleared tissue and of in vivo perfusion predicts drug uptake and treatment responses in tumours
A d'Esposito, PW Sweeney, M Ali, M Saleh… - Nature Biomedical …, 2018 - nature.com
Understanding the uptake of a drug by diseased tissue, and the drug's subsequent
spatiotemporal distribution, are central factors in the development of effective targeted …
spatiotemporal distribution, are central factors in the development of effective targeted …
Computational approaches to modelling and optimizing cancer treatment
TO McDonald, YC Cheng, C Graser, PB Nicol… - Nature Reviews …, 2023 - nature.com
Computational models can be applied to optimize treatment schedules and model treatment
responses in cancer therapy. In this Review, we provide an overview of such computational …
responses in cancer therapy. In this Review, we provide an overview of such computational …