Until the turn of the millennium, laminitis was largely considered a discrete disease entity
with a common pathophysiology, regardless of the inciting cause. Ischemia was implicated …

Acute diarrhea associated with colitis or typhlocolitis is a major cause of morbidity in horses
and is life-threatening. Clinical signs of colic, hypovolemia, and endotoxemia result from …

Laminitis is a severely debilitating, life-threatening disorder affecting the dermal and
epidermal tissues of the equine digit (Table 1). The development of laminitis occurs as a …

Acute laminitis has been defined as the period beginning with the onset of clinical signs
(increased hoof temperature, increased digital pulse amplitude, shifting of weight, lameness) …

Sepsis is a major cause of death in neonatal foals and, in recent years, significant progress
in the understanding of the underlying pathophysiology has been made. To achieve a …

Research demonstrating insulin's causal role in endocrinopathic laminitis has greatly
advanced understanding of equine laminitis. However, the degree to which this knowledge …

Background In the oligofructose (OF) model of sepsis‐related laminitis (SRL), digital
hypothermia (“cryotherapy”) initiated before the onset of clinical signs is reported not only to …

The treatment of laminitis has been fraught with confusion and controversy for several
decades, mainly because of a lack of understanding of the pathophysiology of the disease …

Background Equine post‐operative morbidity represents a significant concern for both
veterinary surgeons and horse owners. Objectives To estimate the prevalence of post …

Despite ongoing research and a widening range of treatment options, laminitis remains a
severely damaging condition with poorly understood pathophysiology. Results obtained …