Alpha-1 antitrypsin deficiency (AATD) is a rare genetic disorder characterised by reduced
levels of circulating alpha-1 antitrypsin and an increased risk of lung and liver disease …

Abstract Alpha1-antitrypsin deficiency (AATD) is a rare autosomal recessive disease
associated with the homozygous Z variant of the SERPINA1 gene. Clinical expression of …

Background The Spanish registry of α1-antitrypsin deficiency (AATD) integrated in the
European Alpha-1 Research Collaboration (EARCO) provides information about the …

Abstract Background The PI* S variant is one of the most prevalent mutations within alpha-1
antitrypsin deficiency (AATD). The risk of developing AATD-related lung disease in …

Abstract Alpha-1 antitrypsin deficiency (AATD) is a rare and underdiagnosed disease that is
associated with the development of liver disease in adults and children and pulmonary …

Background Alpha-1 antitrypsin deficiency (AATD) is a rare disease that is associated with
an increased risk of pulmonary emphysema. The European AATD Research Collaboration …

Background: Alpha-1 antitrypsin deficiency (AATD) is an often-overlooked genetic condition
that makes individuals susceptible to early onset of chronic obstructive pulmonary disease …

Background Although bronchiectasis has been recognised as a feature of some patients
with Alpha1-Antitrypsin deficiency the prevalence and characteristics are not widely known …

Background Sex and gender influence many aspects of chronic obstructive pulmonary
disease (COPD). Limited data are available on this topic in alpha-1 antitrypsin deficiency …

The EARCO registry contains information on> 1000 patients with AATD from 15 countries.
The demographic characteristics and the disease characteristics are not significantly …